Cargo Delivery into the Brain by in vivo identified Transport Peptides.

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作者： Eduard,Urich ^[1] ; Roland,Schmucki ^[2] ; Nadine,Ruderisch ^[1] ; Eric,Kitas ^[3] ; Ulrich,Certa ^[2] ; Helmut,Jacobsen ^[1] ; Christophe,Schweitzer ^[1] ; Alessandra,Bergadano ^[2] ; Martin,Ebeling ^[2] ; Hansruedi,Loetscher ^[1] ; Per-Ola,Freskgård ^[1]

作者单位： Neuroscience Discovery and Translation Area, Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Basel, Switzerland. ^[1] Pharmaceutical Sciences, Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Basel, Switzerland. ^[2] Medicinal Chemistry, Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Basel, Switzerland. ^[3]

主题词氨基酸特征结构(Amino Acid Motifs);氨基酸序列(Amino Acid Sequence);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);动物(Animals);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);细菌噬菌体T7(Bacteriophage T7);生物转运(Biological Transport);血脑屏障(Blood-Brain Barrier);脑(Brain);肽库(Peptide Library);肽类(Peptides);位置特异性得分矩阵(Position-Specific Scoring Matrices);大鼠(Rats);结果可重复性(Reproducibility of Results)

DOI 10.1038/srep14104

PMID 26411801

发布时间 2019-12-10

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Cargo Delivery into the Brain by in vivo identified Transport Peptides.

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Cargo Delivery into the Brain by in vivo identified Transport Peptides.

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