Design, synthesis and biological evaluation of 3-aryl-rhodanine benzoic acids as anti-apoptotic protein Bcl-2 inhibitors.
第一作者:
Huansheng,Fu
第一单位:
Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmacy, Shandong University, 44 West Wenhua Rd, Ji'nan 250012, PR China.
作者:
主题词
抗肿瘤药(Antineoplastic Agents);苯甲酸盐类(Benzoates);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);绕丹宁(Rhodanine);磺胺类(Sulfonamides);噻唑类(Thiazoles);bcl-X蛋白质(bcl-X Protein)
DOI
10.1016/j.bmcl.2015.09.051
PMID
26421995
发布时间
2015-10-31
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