The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature.

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作者： Marina,Díaz-Beyá ^[1] ; Salut,Brunet ^[2] ; Josep,Nomdedéu ^[2] ; Marta,Pratcorona ^[3] ; Anna,Cordeiro ^[2] ; David,Gallardo ^[4] ; Lourdes,Escoda ^[1] ; Mar,Tormo ^[2] ; Inmaculada,Heras ^[5] ; Josep Maria,Ribera ^[6] ; Rafael,Duarte ^[7] ; María Paz Queipo,de Llano ^[8] ; Joan,Bargay ^[9] ; Antonia,Sampol ^[2] ; Meritxell,Nomdedeu ^[10] ; Ruth M,Risueño ^[11] ; Montserrat,Hoyos ^[12] ; Jorge,Sierra ^[13] ; Mariano,Monzo ^[14] ; Alfons,Navarro ^[1] ; Jordi,Esteve ^[2] ; Cooperative AML group CETLAM ^[3]

作者单位： Hematology Department, Hospital Clinic, Institut d'Investigacions Bomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. ^[1] Josep Carreras Leukemia Research Institute (IJC), Barcelona, Spain. ^[2] Hematology Service, Institut d'Investigació Biomèdica Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Banc de Sang i Teixits de Catalunya, Spain. ^[3] Laboratory of Hematology Service, Institut d'Investigació Biomèdica Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain. ^[4] Molecular Oncology and Embryology Laboratory, Human Anatomy Unit, School of Medicine, University of Barcelona, IDIBAPS, Barcelona, Spain. ^[5] Hematology Department, Catalan Institute of Oncology (ICO), Girona, Spain. ^[6] Hematology Department, Hospital Joan XXIII, Tarragona, Spain. ^[7] Hematology Department, Hospital Clínico, Valencia, Spain. ^[8] University Hospital Morales Meseguer, Murcia, Spain. ^[9] Hematology Department, Catalan Institute of Oncology (ICO), Hospital Germans Trias i Pujol, Badalona, Spain. ^[10] Department of Hematology, Catalan Institute of Oncology (ICO), Hospital Duran i Reynals, L'Hospitalet de Llobregat, Barcelona, Spain. ^[11] Hospital Virgen de la Victoria, Málaga, Spain. ^[12] Hospital de Son Llàtzer, Palma de Mallorca, Spain. ^[13] Hospital Son Espases, Palma de Mallorca, Spain. ^[14] University of Barcelona, Barcelona, Spain. ^[15]

关键词 AML HOTAIRM HOX lincRNA lncRNA