Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth.
第一单位:
The Vontz Center for Molecular Studies, Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA.
作者:
医学主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);组蛋白脱乙酰基酶类(Histone Deacetylases);男(雄)性(Male);膜蛋白质类(Membrane Proteins);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);多发性骨髓瘤(Multiple Myeloma);p52亚基NF-κB(NF-kappa B p52 Subunit);磷酰化(Phosphorylation);原癌基因蛋白质类(Proto-Oncogene Proteins);阻遏蛋白质类(Repressor Proteins);转录因子RelB(Transcription Factor RelB)
DOI
10.1038/ncomms9428
PMID
26455434
发布时间
2022-03-30
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Nature communications
8428页
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