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Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.

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第一作者: Sonia,Mulero-Navarro
第一单位: The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
作者单位: The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. [1] The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. [2] Instituto Cajal-Consejo Superior de Investigaciones Científicas, Madrid 28002, Spain. [3] Department of Biochemistry, University of Puerto Rico School of Medicine, San Juan, PR 00936, USA. [4] Buck Institute for Research on Aging, Novato, CA 94945, USA. [5] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. [6] The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. [7] The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. [8] Département de Génétique, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Robert Debré, 75019 Paris, France; INSERM UMR_S1131, Institut Universitaire d'Hématologie, Université Paris Diderot, Paris-Sorbonne-Cité, 75205 Paris, France. [9] Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. [10] Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. [11] Université Paul Sabatier-M2CHRNRS, 31062 Toulouse, France. [12] Dipartimento di Ematologia, Oncologia e Medicina Molecolare, Istituto Superiore di Sanità, Rome 00161, Italy. [13] Dipartimento di Ematologia, Oncologia e Medicina Molecolare, Istituto Superiore di Sanità, Rome 00161, Italy; Area di Ricerca "Malattie Genetiche e Malattie Rare," Ospedale Pediatrico Bambino Gesù, Rome 00165, Italy. [14] The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: bruce.gelb@mssm.edu. [15]
DOI 10.1016/j.celrep.2015.09.019
PMID 26456833
发布时间 2025-05-29
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