The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.
第一作者:
Barbara,Renga
第一单位:
Department of Surgical and Biomedical Sciences, Section of gastroenterology, University of Perugia, Perugia, Italy.
作者:
主题词
艾滋病疫苗(AIDS Vaccines);动物(Animals);细胞, 培养的(Cells, Cultured);胆固醇(Cholesterol);HIV(HIV);Hep G2细胞(Hep G2 Cells);肝细胞(Hepatocytes);人类(Humans);脂类代谢(Lipid Metabolism);肝(Liver);中介复合体亚基1(Mediator Complex Subunit 1);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);孤儿核受体(Orphan Nuclear Receptors);肽碎片(Peptide Fragments);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);重组蛋白质类(Recombinant Proteins);STAT转录因子类(STAT Transcription Factors);信号传导(Signal Transduction);胆固醇调节元件结合蛋白质1(Sterol Regulatory Element Binding Protein 1);反式激活因子类(Trans-Activators);转录激活(Transcriptional Activation);env基因产物, 人免疫缺陷病毒(env Gene Products, Human Immunodeficiency Virus)
DOI
10.1038/srep15403
PMID
26469385
发布时间
2019-04-16
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