Synthesis of some new amide-linked bipyrazoles and their evaluation as anti-inflammatory and analgesic agents.

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作者： Wissam H,Faour ^[1] ; Mohamed,Mroueh ^[2] ; Costatantine F,Daher ^[3] ; Rasha Y,Elbayaa ^[4] ; Hanan M,Ragab ^[5] ; Asser I,Ghoneim ^[4] ; Ahmed I,El-Mallah ^[6] ; Hayam M A,Ashour ^[7]

作者单位： a School of Medicine, Lebanese American University , Byblos , Lebanon . ^[1] b Department of Pharmaceutical Sciences , School of Pharmacy, Lebanese American University , Byblos , Lebanon . ^[2] c Department of Natural Sciences , School of Arts and Sciences, Lebanese American University , Byblos , Lebanon . ^[3] d Department of Pharmaceutical Chemistry , Faculty of Pharmacy, Alexandria University , Alexandria , Egypt . ^[4] e Department of Analytical & Pharmaceutical Chemistry , Faculty of Pharmacy & Drug Manufacturing, Pharos University in Alexandria , Alexandria , Egypt . ^[5] f Department of Pharmacology and Therapeutics , Faculty of Pharmacy, Beirut Arab University , Beirut , Lebanon . ^[6] g Department of Pharmacology and Toxicology , Faculty of Pharmacy, Damanhour University , Damanhour , Egypt , and. ^[7] h Department of Pharmacology , Faculty of Pharmacy & Drug Manufacturing, Pharos University in Alexandria , Alexandria , Egypt. ^[8]

关键词 Anti-inflammatory COX-2 analgesic iNOS

主题词酰胺类(Amides);镇痛药(Analgesics);消炎药(Anti-Inflammatory Agents);药物评价, 临床前(Drug Evaluation, Preclinical);吡唑类(Pyrazoles);光谱分析(Spectrum Analysis)

DOI 10.3109/14756366.2015.1094469

PMID 26482802

发布时间 2022-03-17

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