The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.

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第一作者： Alexander,Koppara

第一单位： Department of Psychiatry, University of Bonn, Germany.

作者： Alexander,Koppara ^[1] ; Steffen,Wolfsgruber ^[2] ; Luca,Kleineidam ^[1] ; Klaus,Schmidtke ^[2] ; Lutz,Frölich ^[1] ; Alexander,Kurz ^[2] ; Stefanie,Schulz ^[3] ; Harald,Hampel ^[4] ; Isabella,Heuser ^[5] ; Oliver,Peters ^[6] ; Friedel M,Reischies ^[7] ; Holger,Jahn ^[8] ; Christian,Luckhaus ^[8] ; Michael,Hüll ^[8] ; Hermann-Josef,Gertz ^[9] ; Johannes,Schröder ^[10] ; Johannes,Pantel ^[11] ; Otto,Rienhoff ^[12] ; Eckart,Rüther ^[13] ; Fritz,Henn ^[14] ; Jens,Wiltfang ^[15] ; Wolfgang,Maier ^[16] ; Frank,Jessen ^[17] ; Johannes,Kornhuber ^[16] ; Michael,Wagner ^[1]

作者单位： Department of Psychiatry, University of Bonn, Germany. ^[1] German Center for Neurodegenerative Diseases, Bonn, Germany. ^[2] Center for Geriatric Medicine, Ortenau Klinikum, Offenburg-Gengenbach, Germany. ^[3] Department of Gerontopsychiatry, Central Institute of Mental Health, Mannheim, Germany. ^[4] Department of Psychiatry, Technical University of Munich, Germany. ^[5] Department of Neurology, University of Aachen, Germany. ^[6] Department of Neurology, Université Pierre et Marie Curie (Sorbonne), and AXA Research Fund & UPMC Chair, Paris, France. ^[7] Department of Psychiatry, Charité Berlin, Campus Benjamin Franklin, Berlin, Germany. ^[8] Department of Psychiatry, University of Hamburg, Germany. ^[9] Department of Psychiatry, University of Düsseldorf, Germany. ^[10] Center for Psychiatry, Clinic for Geronto- and Neuropsychiatry Emmendingen and Dep. of Psychiatry, University of Freiburg, Germany. ^[11] Department of Psychiatry, University of Leipzig, Germany. ^[12] Section for Geriatric Psychiatry/Institute of Gerontology, University of Heidelberg, Germany. ^[13] Institute of General Medicine University of Frankfurt, Frankfurt am Main, Germany. ^[14] Department of Medical Informatics, University of Göttingen, Germany. ^[15] Department of Psychiatry and Psychotherapy, University of Göttingen, Germany. ^[16] Ichan School of Medicine at Mt. Sinai, New York, USA. ^[17] Department of Psychiatry, Medical Faculty University of Cologne, Germany. ^[18] Department of Psychiatry, Friedrich-Alexander-University Erlangen, Germany. ^[19]

关键词 CSF AD biomarker signature delta model incident dementia mild cognitive impairment