Halting pro-survival autophagy by TGFβ inhibition in bone marrow fibroblasts overcomes bortezomib resistance in multiple myeloma patients.

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第一作者： M A,Frassanito

第一单位： Department of Biomedical Sciences and Human Oncology, General Pathology Unit, University of Bari Medical School, Bari, Italy.

作者： M A,Frassanito ^[1] ; K,De Veirman ^[2] ; V,Desantis ^[3] ; L,Di Marzo ^[3] ; D,Vergara ^[4] ; S,Ruggieri ^[5] ; T,Annese ^[5] ; B,Nico ^[5] ; E,Menu ^[2] ; I,Catacchio ^[3] ; R,Ria ^[3] ; V,Racanelli ^[3] ; M,Maffia ^[4] ; E,Angelucci ^[6] ; D,Derudas ^[6] ; R,Fumarulo ^[1] ; F,Dammacco ^[3] ; D,Ribatti ^[5] ; K,Vanderkerken ^[2] ; A,Vacca ^[3]

作者单位： Department of Biomedical Sciences and Human Oncology, General Pathology Unit, University of Bari Medical School, Bari, Italy. ^[1] Department of Hematology and Immunology, Myeloma Center Brussels, Vrije Universiteit Brussel, Brussels, Belgium. ^[2] Department of Biomedical Sciences and Human Oncology, Unit of Internal Medicine and Clinical Oncology, University of Bari Medical School, Bari, Italy. ^[3] Department of Biological and Environmental Sciences and Technologies, University of Salento, Laboratory of Clinical Proteomics, "Giovanni Paolo II" Hospital, ASL-Lecce, Italy. ^[4] Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Medical School, Bari, Italy. ^[5] Department of Haematology, Businco Hospital, Cagliari, Italy. ^[6]