A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients.

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作者： Ann J,Ligocki ^[1] ; Jacqueline R,Rivas ^[1] ; William H,Rounds ^[1] ; Alyssa A,Guzman ^[1] ; Min,Li ^[1] ; Melania,Spadaro ^[2] ; Lauren,Lahey ^[3] ; Ding,Chen ^[1] ; Paul M,Henson ^[1] ; Donna,Graves ^[1] ; Benjamin M,Greenberg ^[1] ; Elliot M,Frohman ^[1] ; E Sally,Ward ^[4] ; William,Robinson ^[3] ; Edgar,Meinl ^[2] ; Charles L,White ^[5] ; Ann M,Stowe ^[1] ; Nancy L,Monson ^[6]

作者单位： Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[1] Institute of Clinical Neuroimmunology, Ludwig-Maximilian-University, Munich, Germany. ^[2] Department of Immunology and Rheumatology, Stanford University, CA, USA. ^[3] Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[4] Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[5] Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA nancy.monson@utsouthwestern.edu. ^[6]

关键词 B cell autoantibody clinically isolated syndrome gray matter multiple sclerosis myelin tracts

主题词成年人(Adult);动物(Animals);自身抗体(Autoantibodies);自身免疫(Autoimmunity);B-淋巴细胞(B-Lymphocytes);脑(Brain);脑脊髓炎, 自身免疫性, 实验性(Encephalomyelitis, Autoimmune, Experimental);女(雌)性(Female);糖蛋白类(Glycoproteins);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);中年人(Middle Aged);多发性硬化, 复发缓解性(Multiple Sclerosis, Relapsing-Remitting);少突神经胶质(Oligodendroglia);重组蛋白质类(Recombinant Proteins);卒中(Stroke);青年人(Young Adult)

DOI 10.1177/1759091415609613

PMID 26489686

发布时间 2018-11-13

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A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients.

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A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients.

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