Valproic acid modulates radiation-enhanced matrix metalloproteinase activity and invasion of breast cancer cells.

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第一作者： Francisco,Artacho-Cordón

第一单位： a Department of Radiology and Physical Medicine , University of Granada , Granada , Spain.

作者： Francisco,Artacho-Cordón ^[1] ; Sandra,Ríos-Arrabal ^[2] ; María Auxiliadora,Olivares-Urbano ^[1] ; Katja,Storch ^[2] ; Ellen,Dickreuter ^[3] ; José Antonio,Muñoz-Gámez ^[1] ; Josefa,León ^[4] ; Irene,Calvente ^[5] ; Pablo,Torné ^[6] ; María del Mar,Salinas ^[7] ; Nils,Cordes ^[8] ; María Isabel,Núñez ^[4]

作者单位： a Department of Radiology and Physical Medicine , University of Granada , Granada , Spain. ^[1] b Biosanitary Institute of Granada (ibs.GRANADA), University Hospitals of Granada/University of Granada , Granada , Spain. ^[2] c Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada , Armilla, Granada , Spain. ^[3] d OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, and Helmholtz-Zentrum Dresden-Rossendorf , Dresden , Germany. ^[4] e Department of Radiation Oncology , University Hospital Carl Gustav Carus, Technische Universität Dresden , Dresden , Germany. ^[5] f German Cancer Consortium (DKTK), Dresden, Germany. ^[6] g German Cancer Research Center (DKFZ) , Heidelberg , Germany. ^[7] h Institute of Radiooncology, Helmholtz-Zentrum Dresden-Rossendorf , Dresden , Germany. ^[8] i CIBER on hepatic and digestive diseases (CIBEREHD) , Spain. ^[9] j General Surgery Management Unit, San Cecilio University Hospital , Granada , Spain. ^[10]

关键词 Matrix metalloproteinases breast cancer epigenetic regulation histone deacetylases invasion ionizing radiation tumour microenvironment