作者：
Alexandre,Wagschal [1]
;
S Hani,Najafi-Shoushtari [2]
;
Lifeng,Wang [1]
;
Leigh,Goedeke [2]
;
Sumita,Sinha [1]
;
Andrew S,deLemos [2]
;
Josh C,Black [3]
;
Cristina M,Ramírez [4]
;
Yingxia,Li [5]
;
Ryan,Tewhey [1]
;
Ida,Hatoum [6]
;
Naisha,Shah [3]
;
Yong,Lu [7]
;
Fjoralba,Kristo [8]
;
Nikolaos,Psychogios [9]
;
Vladimir,Vrbanac [10]
;
Yi-Chien,Lu [11]
;
Timothy,Hla [11]
;
Rafael,de Cabo [1]
;
John S,Tsang [4]
;
Eric,Schadt [12]
;
Pardis C,Sabeti [13]
;
Sekar,Kathiresan [13]
;
David E,Cohen [14]
;
Johnathan,Whetstine [11]
;
Raymond T,Chung [15]
;
Carlos,Fernández-Hernando [8]
;
Lee M,Kaplan [9]
;
Andre,Bernards [4]
;
Robert E,Gerszten [6]
;
Anders M,Näär [8]
作者单位：
Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.
[1]
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
[2]
Section of Comparative Medicine, Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
[3]
Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
[4]
Liver Center and Gastrointestinal Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
[5]
Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
[6]
Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
[7]
Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.
[8]
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.
[9]
Obesity, Metabolism and Nutrition Institute and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
[10]
Systems Genomics and Bioinformatics Unit, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
[11]
Harvard University Center for AIDS Research, Cambridge, Massachusetts USA.
[12]
Center for Vascular Biology, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, Cornell University, New York, New York, USA.
[13]
Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.
[14]
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
[15]
Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
[16]
主题词
动物(Animals);载脂蛋白E类(Apolipoproteins E);胆固醇(Cholesterol);胆固醇, HDL(Cholesterol, HDL);胆固醇, LDL(Cholesterol, LDL);血脂异常(Dyslipidemias);全基因组关联研究(Genome-Wide Association Study);内环境稳定(Homeostasis);人类(Humans);脂蛋白类(Lipoproteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);微RNAs(MicroRNAs);多态性, 单核苷酸(Polymorphism, Single Nucleotide);受体, LDL(Receptors, LDL);甘油三酯类(Triglycerides)
DOI
10.1038/nm.3980
PMID
26501192
发布时间
2018-11-13
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