Synthesis, Molecular Structure, Metabolic Stability and QSAR Studies of a Novel Series of Anticancer N-Acylbenzenesulfonamides.

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作者： Beata,Żołnowska ^[1] ; Jarosław,Sławiński ^[2] ; Mariusz,Belka ^[3] ; Tomasz,Bączek ^[4] ; Anna,Kawiak ^[5] ; Jarosław,Chojnacki ^[6] ; Aneta,Pogorzelska ^[7] ; Krzysztof,Szafrański ^[8]

作者单位： Department of Organic Chemistry, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland. zolnowska@gumed.edu.pl. ^[1] Department of Organic Chemistry, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland. jaroslaw@gumed.edu.pl. ^[2] Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland. mariusz.belka@gumed.edu.pl. ^[3] Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland. tbaczek@gumed.edu.pl. ^[4] Department of Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, ul. Kładki 24, 80-822 Gdańsk, Poland. kawiak@biotech.ug.pl. ^[5] Department of Human Physiology, Medical University of Gdańsk, ul. Tuwima 15, 80-210 Gdańsk, Poland. kawiak@biotech.ug.pl. ^[6] Department of Inorganic Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland. jarekch@pg.gda.pl. ^[7] Department of Organic Chemistry, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland. anetapogorzelska@gumed.edu.pl. ^[8] Department of Organic Chemistry, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland. k.szafranski@gumed.edu.pl. ^[9]

关键词 QSAR anticancer metabolic stability sulfonamide synthesis