MicroRNA-129-1 acts as tumour suppressor and induces cell cycle arrest of GBM cancer cells through targeting IGF2BP3 and MAPK1.

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第一作者： Fatemeh,Kouhkan

第一单位： Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran.

作者： Fatemeh,Kouhkan ^[1] ; Naser,Mobarra ^[2] ; Mina,Soufi-Zomorrod ^[3] ; Farid,Keramati ^[1] ; Seyed Mohammad Ali,Hosseini Rad ^[1] ; Mehrnoosh,Fathi-Roudsari ^[4] ; Rezvan,Tavakoli ^[1] ; Athena,Hajarizadeh ^[1] ; Said,Ziaei ^[5] ; Reyhaneh,Lahmi ^[6] ; Hamed,Hanif ^[7] ; Masoud,Soleimani ^[8]

作者单位： Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran. ^[1] Metabolic Disorders Research Center, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. ^[2] Department of Hematology, School of Medicine, Tarbiat Modares University, Tehran, Iran. ^[3] National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran. ^[4] Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran Department of Basic Sciences, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ^[5] Department of Neuroscience, Aging and Stem Cell Research Center, Sanford-Burnham Medical Research Institute, La Jolla, California, USA. ^[6] Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. ^[7] Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran Department of Hematology, School of Medicine, Tarbiat Modares University, Tehran, Iran. ^[8]

关键词 Cancer: CNS Cell biology Gene therapy MicroRNA Neuro oncology