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首页> Brain and behavior> Selective inhibition of dopamine-beta-hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex.

Selective inhibition of dopamine-beta-hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex.

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作者： Paola,Devoto ^[1] ; Giovanna,Flore ^[2] ; Pierluigi,Saba ^[3] ; Roberto,Frau ^[4] ; Gian L,Gessa ^[5]

作者单位： Department of Biomedical Sciences Section of Neuroscience and Clinical Pharmacology University of Cagliari Cagliari Italy ; "Guy Everett Laboratory" University of Cagliari Cagliari Italy ; Center of Excellence "Neurobiology of Addiction" University of Cagliari Cagliari Italy. ^[1] Department of Medical Sciences University of Cagliari Cagliari Italy. ^[2] Department of Biomedical Sciences Section of Neuroscience and Clinical Pharmacology University of Cagliari Cagliari Italy. ^[3] Department of Biomedical Sciences Section of Neuroscience and Clinical Pharmacology University of Cagliari Cagliari Italy ; "Guy Everett Laboratory" University of Cagliari Cagliari Italy. ^[4] Department of Biomedical Sciences Section of Neuroscience and Clinical Pharmacology University of Cagliari Cagliari Italy ; "Guy Everett Laboratory" University of Cagliari Cagliari Italy ; National Research Council CNR, Institute of Neuroscience Cagliari Italy. ^[5]

关键词 cocaine corelease microdialysis nepicastat α2‐adrenoceptor

主题词动物(Animals);可卡因(Cocaine);多巴胺(Dopamine);多巴胺β羟化酶(Dopamine beta-Hydroxylase);酶抑制剂(Enzyme Inhibitors);咪唑类(Imidazoles);注射, 脑室内(Injections, Intraventricular);男(雄)性(Male);微透析(Microdialysis);去甲肾上腺素(Norepinephrine);额叶前皮质(Prefrontal Cortex);突触前末梢(Presynaptic Terminals);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);自我遵嘱服药(Self Administration);硫酮类(Thiones)

DOI 10.1002/brb3.393

PMID 26516613

发布时间 2022-03-11

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