The activity of RTA2, a downstream effector of the calcineurin pathway, is required during tunicamycin-induced ER stress response in Candida albicans.

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第一作者： Edwina,Thomas

第一单位： Yeast Molecular Genetics Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi-110067, India.

作者： Edwina,Thomas ^[1] ; Shabnam,Sircaik ^[1] ; Elvira,Roman ^[2] ; Jean-Michel,Brunel ^[3] ; Atul K,Johri ^[1] ; Jesús,Pla ^[2] ; Sneh L,Panwar ^[4]

作者单位： Yeast Molecular Genetics Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi-110067, India. ^[1] Departamento de Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain. ^[2] Centre de Recherche en Cancérologie de Marseille, Laboratory of Integrative Structural & Chemical Biology, UMR CNRS F-7258, France. ^[3] Yeast Molecular Genetics Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi-110067, India sneh@mail.jnu.ac.in. ^[4]

关键词 Candida albicans ER stress Hac1 RTA2 calcineurin unfolded protein response

主题词抗感染药(Anti-Infective Agents);白色念珠菌(Candida albicans);真菌蛋白质类(Fungal Proteins);基因缺失(Gene Deletion);衣霉素(Tunicamycin);非折叠蛋白质应答(Unfolded Protein Response)

DOI 10.1093/femsyr/fov095

PMID 26518191

发布时间 2015-11-20

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