Variability and anatomical specificity of the orbitofrontothalamic fibers of passage in the ventral capsule/ventral striatum (VC/VS): precision care for patient-specific tractography-guided targeting of deep brain stimulation (DBS) in obsessive compulsive disorder (OCD).

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作者： Nikolaos,Makris ^[1] ; Yogesh,Rathi ^[2] ; Palig,Mouradian ^[3] ; Giorgio,Bonmassar ^[4] ; George,Papadimitriou ^[5] ; Wingkwai I,Ing ^[6] ; Edward H,Yeterian ^[5] ; Marek,Kubicki ^[5] ; Emad N,Eskandar ^[5] ; Lawrence L,Wald ^[5] ; Qiuyun,Fan ^[7] ; Aapo,Nummenmaa ^[5] ; Alik S,Widge ^[6] ; Darin D,Dougherty ^[5]

作者单位： Departments of Psychiatry, Neurology, Neurosurgery and Radiology, Center for Morphometric Analysis, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA, 02129, USA. nikos@cma.mgh.harvard.edu. ^[1] Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. nikos@cma.mgh.harvard.edu. ^[2] McLean Imaging Center, McLean Hospital, Harvard Medical School, Boston, MA, USA. nikos@cma.mgh.harvard.edu. ^[3] Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA. nikos@cma.mgh.harvard.edu. ^[4] Departments of Psychiatry, Neurology, Neurosurgery and Radiology, Center for Morphometric Analysis, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA, 02129, USA. ^[5] Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ^[6] Department of Psychology, Colby College, Waterville, ME, USA. ^[7] Picower Institute for Learning & Memory, Massachusetts Institute of Technology, Cambridge, MA, USA. ^[8]

关键词 Connectome Deep brain stimulation (DBS)Diffusion tensor imaging Diffusion tractography Obsessive-compulsive disorder (OCD)Tractography-guided DBS