Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.-论文-万方医学网

第一作者： Dominik,Stammler

第一单位： Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg 69120, Germany;

作者： Dominik,Stammler ^[1] ; Tatjana,Eigenbrod ^[1] ; Sarah,Menz ^[2] ; Julia S,Frick ^[2] ; Matthew J,Sweet ^[3] ; Melanie R,Shakespear ^[3] ; Jonathan,Jantsch ^[4] ; Isabel,Siegert ^[5] ; Sabine,Wölfle ^[1] ; Julian D,Langer ^[6] ; Ina,Oehme ^[7] ; Liliana,Schaefer ^[8] ; Andre,Fischer ^[9] ; Judith,Knievel ^[10] ; Klaus,Heeg ^[1] ; Alexander H,Dalpke ^[1] ; Konrad A,Bode ^[11]

作者单位： Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg 69120, Germany; ^[1] Institute of Medical Microbiology and Hygiene, University of Tübingen, Tübingen 70276, Germany; ^[2] Institute for Molecular Bioscience, University of Queensland, Brisbane, St. Lucia, Queensland 4072, Australia; ^[3] Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg 93053, Germany; Institute of Microbiology, University of Erlangen-Nuremberg, Erlangen 91054, Germany; ^[4] Institute of Microbiology, University of Erlangen-Nuremberg, Erlangen 91054, Germany; ^[5] Department of Molecular Membrane Biology, Max-Planck-Institute for Biophysics, Frankfurt 60438, Germany; ^[6] Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center, Heidelberg 69120, Germany; ^[7] Institute of Pharmacology, Goethe University Frankfurt, Frankfurt 60590, Germany; ^[8] German Center for Neurodegenerative Diseases, Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen 37077, Germany; and. ^[9] Department of Gastroenterology, Hepatology, and Infectious Disease, University Hospital, Heinrich Heine University of Düsseldorf, Düsseldorf 40225, Germany. ^[10] Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg 69120, Germany; konrad.bode@uni-heidelberg.de. ^[11]

医学主题词动物(Animals);骨髓细胞(Bone Marrow Cells);载体蛋白质类(Carrier Proteins);半胱氨酸天冬氨酸蛋白酶1(Caspase 1);半胱氨酸天冬氨酸蛋白酶8(Caspase 8);半胱氨酸天冬氨酸蛋白酶(Caspases);半胱氨酸天冬氨酸蛋白酶类, 起始(Caspases, Initiator);细胞, 培养的(Cells, Cultured);结肠炎(Colitis);树突细胞(Dendritic Cells);硫酸葡聚糖(Dextran Sulfate);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);组蛋白脱乙酰基酶类(Histone Deacetylases);炎性体(Inflammasomes);白细胞介素1β(Interleukin-1beta);脂多糖类(Lipopolysaccharides);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout)

DOI 10.4049/jimmunol.1501195

PMID 26519528

发布时间 2020-12-09

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Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

Journal of immunology (Baltimore, Md.

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Journal of immunology (Baltimore, Md.

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Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

Journal of immunology (Baltimore, Md.

相似文献

同项目论文

Journal of immunology (Baltimore, Md.

相关期刊

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