Global quantification of γH2AX as a triage tool for the rapid estimation of received dose in the event of accidental radiation exposure.

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作者： Muriel,Viau ^[1] ; Isabelle,Testard ^[2] ; Grace,Shim ^[3] ; Luc,Morat ^[4] ; Marie D,Normil ^[5] ; William M,Hempel ^[6] ; Laure,Sabatier ^[7]

作者单位： Commissariat à l'Energie Atomique (CEA), Laboratoire de Radiobiologie et Oncologie (LRO), 18 Route du Panorama - BP6, 92265 Fontenay-aux-Roses, France. Electronic address: muriel.viau@gmail.com. ^[1] CEA Grenoble, Laboratoire de Chimie et Biologie des Métaux, DSV / iRTSV, 17 rue des Martyrs, 38054 Grenoble Cedex 5, France. Electronic address: isabelle.testard@cea.fr. ^[2] Commissariat à l'Energie Atomique (CEA), Laboratoire de Radiobiologie et Oncologie (LRO), 18 Route du Panorama - BP6, 92265 Fontenay-aux-Roses, France. Electronic address: graceshim1@gmail.com. ^[3] Commissariat à l'Energie Atomique (CEA), Laboratoire de Radiobiologie et Oncologie (LRO), 18 Route du Panorama - BP6, 92265 Fontenay-aux-Roses, France. Electronic address: luc.morat@cea.fr. ^[4] Commissariat à l'Energie Atomique (CEA), Laboratoire de Radiobiologie et Oncologie (LRO), 18 Route du Panorama - BP6, 92265 Fontenay-aux-Roses, France. Electronic address: normil.mariedelna@yahoo.fr. ^[5] Commissariat à l'Energie Atomique (CEA), Laboratoire de Radiobiologie et Oncologie (LRO), 18 Route du Panorama - BP6, 92265 Fontenay-aux-Roses, France. Electronic address: william.hempel@cea.fr. ^[6] Commissariat à l'Energie Atomique (CEA), Laboratoire de Radiobiologie et Oncologie (LRO), 18 Route du Panorama - BP6, 92265 Fontenay-aux-Roses, France. Electronic address: laure.sabatier@cea.fr. ^[7]

关键词 Accidental irradiation Biological dosimetry Casualty triage Flow cytometry H2AX phosphorylation Ionizing radiation

主题词细胞, 培养的(Cells, Cultured);DNA断裂, 双链(DNA Breaks, Double-Stranded);流式细胞术(Flow Cytometry);组蛋白类(Histones);人类(Humans);淋巴细胞(Lymphocytes);显微镜检查, 荧光(Microscopy, Fluorescence);磷酰化(Phosphorylation);辐射剂量(Radiation Dosage);放射性有害物质释放(Radioactive Hazard Release);放射测量术(Radiometry);伤病员分拣(Triage)

DOI 10.1016/j.mrgentox.2015.05.009

PMID 26520382

发布时间 2019-08-16

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Mutation research. Genetic toxicology and environmental mutagenesis

2015年793卷

123-31页

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Global quantification of γH2AX as a triage tool for the rapid estimation of received dose in the event of accidental radiation exposure.

Mutation research. Genetic toxicology and environmental mutagenesis

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Global quantification of γH2AX as a triage tool for the rapid estimation of received dose in the event of accidental radiation exposure.

Mutation research. Genetic toxicology and environmental mutagenesis

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Mutation research. Genetic toxicology and environmental mutagenesis

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