Preserved global histone H4 acetylation linked to ETV6-RUNX1 fusion and PAX5 deletions is associated with favorable outcome in pediatric B-cell progenitor acute lymphoblastic leukemia.
作者:
主题词
乙酰化作用(Acetylation);青少年(Adolescent);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);儿童(Child);儿童, 学龄前(Child, Preschool);染色体, 人, 12对(Chromosomes, Human, Pair 12);染色体, 人, 21对(Chromosomes, Human, Pair 21);核心结合因子α2亚基(Core Binding Factor Alpha 2 Subunit);无病生存(Disease-Free Survival);后成说, 遗传(Epigenesis, Genetic);女(雌)性(Female);组蛋白类(Histones);人类(Humans);婴儿(Infant);男(雄)性(Male);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);前体B细胞淋巴母细胞白血病淋巴瘤(Precursor B-Cell Lymphoblastic Leukemia-Lymphoma);预后(Prognosis);比例危险度模型(Proportional Hazards Models);蛋白质加工, 转译后(Protein Processing, Post-Translational);缓解诱导(Remission Induction);易位, 遗传(Translocation, Genetic);治疗结果(Treatment Outcome)
DOI
10.1016/j.leukres.2015.10.006
PMID
26520622
发布时间
2016-11-26
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Leukemia research
1455-61页
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