Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.

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作者： Ende,Zhao ^[1] ; Tomasz,Maj ^[2] ; Ilona,Kryczek ^[1] ; Wei,Li ^[1] ; Ke,Wu ^[1] ; Lili,Zhao ^[2] ; Shuang,Wei ^[1] ; Joel,Crespo ^[2] ; Shanshan,Wan ^[3] ; Linda,Vatan ^[1] ; Wojciech,Szeliga ^[1] ; Irene,Shao ^[1] ; Yin,Wang ^[1] ; Yan,Liu ^[1] ; Sooryanarayana,Varambally ^[1] ; Arul M,Chinnaiyan ^[1] ; Theodore H,Welling ^[1] ; Victor,Marquez ^[4] ; Jan,Kotarski ^[5] ; Hongbo,Wang ^[5] ; Zehua,Wang ^[1] ; Yi,Zhang ^[6] ; Rebecca,Liu ^[7] ; Guobin,Wang ^[2] ; Weiping,Zou ^[8]

作者单位： Department of Surgery, University of Michigan School of Medicine, Ann Arbor, Michigan, USA. ^[1] Department of Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ^[2] Department of Biostatistics, University of Michigan School of Medicine, Ann Arbor, Michigan, USA. ^[3] Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA. ^[4] Department of Pathology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA. ^[5] Chemical Biology Laboratory, Center for Cancer Research, NCI-Frederick, Frederick, Maryland, USA. ^[6] The First Department of Gynecologic Oncology and Gynecology, Medical University of Lublin, Lublin, Poland. ^[7] Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ^[8] Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, USA. ^[9] Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Arbor, Michigan, USA. ^[10] Graduate Programs in Immunology and Cancer Biology, University of Michigan, Ann Arbor, Michigan, USA. ^[11] Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan, USA. ^[12]