A selective delta opioid receptor antagonist based on a stilbene core.

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作者： Alyssa M,Hartung ^[1] ; Hernan A,Navarro ^[2] ; David F,Wiemer ^[1] ; Jeffrey D,Neighbors ^[3]

作者单位： Department of Chemistry, The University of Iowa, Chemistry Building, Iowa City, IA 52242-1294, United States. ^[1] Discovery Sciences, RTI International, Research Triangle Park, NC 27709, United States. ^[2] Department of Chemistry, The University of Iowa, Chemistry Building, Iowa City, IA 52242-1294, United States; Department of Pharmacology, Pennsylvania State University Hershey College of Medicine, Hershey, PA 17033, United States; Penn State Hershey Cancer Institute, Hershey, PA 17033, United States. ^[3]

关键词 Delta receptor Directed ortho metalation Docking Opioid Pawhuskin

主题词人类(Humans);分子结构(Molecular Structure);麻醉品拮抗药(Narcotic Antagonists);受体, 阿片样, δ(Receptors, Opioid, delta);二苯乙烯类(Stilbenes);萜类(Terpenes)

DOI 10.1016/j.bmcl.2015.10.059

PMID 26525865

发布时间 2018-11-13

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