Effects of the 34C>T Variant of the AMPD1 Gene on Immune Function, Multi-Organ Dysfunction, and Mortality in Sepsis Patients.-论文-万方医学网

作者： Bart P,Ramakers ^[1] ; Evangelos J,Giamarellos-Bourboulis ^[2] ; Chronis,Tasioudis ^[3] ; Marieke J H,Coenen ; Matthijs,Kox ; Sita H,Vermeulen ; Johanne M,Groothuismink ; Johannes G,van der Hoeven ; Christina,Routsi ; Athina,Savva ; Athanassios,Prekates ; Filia,Diamantea ; Dimitrios,Sinapidis ; Paul,Smits ; Konstantinos,Toutouzas ; Niels P,Riksen ; Peter,Pickkers ; Hellenic Sepsis Study Group

作者单位： *Department of Pharmacology and Toxicology †Intensive Care Medicine ‡Internal Medicine §Human Genetics ¶Anesthesiology ^[1] Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands #4th Department of Internal Medicine, University of Athens, Medical School, Athens **Intensive Care Unit, "G. Gennimatas" General Hospital, Thessaloniki ††1st Department of Critical Care Medicine, University of Athens, Medical School ‡‡Intensive Care Unit, Tzaneion General Hospital of Piraeus §§Department of Respiratory Medicine, "Sismanogleion" General Hospital ¶¶Department of Therapeutics, Alexandra General Hospital ^[2] 1st Department of Propedeutic Surgery, University of Athens, Medical School, Athens, Greece. ^[3]

主题词 AMP脱氨酶(AMP Deaminase);腺苷(Adenosine);老年人(Aged);社区获得性感染(Community-Acquired Infections);危重病人医疗(Critical Care);细胞因子类(Cytokines);女(雌)性(Female);基因型(Genotype);人类(Humans);免疫系统(Immune System);免疫, 先天(Immunity, Innate);炎症(Inflammation);男(雄)性(Male);中年人(Middle Aged);单核细胞(Monocytes);多器官功能衰竭(Multiple Organ Failure);肺炎(Pneumonia);肺炎, 呼吸机相关性(Pneumonia, Ventilator-Associated);多态现象, 遗传(Polymorphism, Genetic);多态性, 单核苷酸(Polymorphism, Single Nucleotide);前瞻性研究(Prospective Studies);脓毒症(Sepsis)

DOI 10.1097/SHK.0000000000000456

PMID 26529652

发布时间 2021-12-03

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Effects of the 34C>T Variant of the AMPD1 Gene on Immune Function, Multi-Organ Dysfunction, and Mortality in Sepsis Patients.

Shock (Augusta, Ga.)

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Shock (Augusta, Ga.)

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Effects of the 34C&gt;T Variant of the AMPD1 Gene on Immune Function, Multi-Organ Dysfunction, and Mortality in Sepsis Patients.

Shock (Augusta, Ga.)

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Shock (Augusta, Ga.)

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Effects of the 34C>T Variant of the AMPD1 Gene on Immune Function, Multi-Organ Dysfunction, and Mortality in Sepsis Patients.