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首页> Oncotarget> Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population.

Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population.

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作者： Qianyi,Xiao ^[1] ; Zhi-Jun,Liu ^[2] ; Sha,Tao ^[3] ; Yi-Min,Sun ^[1] ; Deke,Jiang ^[3] ; Hong-Lei,Li ^[4] ; Haitao,Chen ^[2] ; Xu,Liu ^[1] ; Brittany,Lapin ^[4] ; Chi-Hsiung,Wang ^[5] ; S Lilly,Zheng ^[5] ; Jianfeng,Xu ^[4] ; Zhi-Ying,Wu ^[5]

作者单位： Center for Genomic Translational Medicine and Prevention, School of Public Health, Fudan University, Shanghai, China. ^[1] Department of Neurology and Research Center of Neurology in Second Affiliated Hospital, and the Collaborative Innovation Center for Brain Science, Zhejiang University School of Medicine, Hangzhou, China. ^[2] Department of Neurology and Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China. ^[3] State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China. ^[4] Program for Personalized Cancer Care, NorthShore University Health System, Evanston, IL, USA. ^[5] Fudan Institute of Urology, Huashan Hospital, Fudan University, Shanghai, China. ^[6]

关键词 Alzheimer’s disease Gerotarget association genetic risk score risk prediction single nucleotide polymorphism

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);方差分析(Analysis of Variance);病例对照研究(Case-Control Studies);中国(China);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);基因型(Genotype);人类(Humans);男(雄)性(Male);中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);试验预期值(Predictive Value of Tests);危险性评估(Risk Assessment);危险因素(Risk Factors)

DOI 10.18632/oncotarget.6271

PMID 26543236

发布时间 2022-12-07

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Oncotarget

Oncotarget

2015年6卷35期

36955-64页

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