Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.

导出 OA

翻译打印收藏纠错

作者： Yoan,Machado ^[1] ; Regina,Freier ^[1] ; Sandra,Scheiblhofer ^[1] ; Theresa,Thalhamer ^[1] ; Melissa,Mayr ^[1] ; Peter,Briza ^[1] ; Sarina,Grutsch ^[2] ; Linda,Ahammer ^[2] ; Julian E,Fuchs ^[3] ; Hannes G,Wallnoefer ^[3] ; Almedina,Isakovic ^[1] ; Vera,Kohlbauer ^[1] ; Arthur,Hinterholzer ^[1] ; Markus,Steiner ^[1] ; Martin,Danzer ^[4] ; Jutta,Horejs-Hoeck ^[1] ; Fatima,Ferreira ^[1] ; Klaus R,Liedl ^[3] ; Martin,Tollinger ^[2] ; Peter,Lackner ^[1] ; Christopher M,Johnson ^[5] ; Hans,Brandstetter ^[1] ; Josef,Thalhamer ^[1] ; Richard,Weiss ^[6]

作者单位： Department of Molecular Biology, University of Salzburg, Salzburg, Austria. ^[1] Center of Molecular Biosciences & Institute of Organic Chemistry, University of Innsbruck, Innsbruck, Austria. ^[2] Center of Molecular Biosciences & Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria. ^[3] Austrian Red Cross, Blood Transfusion Service for Upper Austria, Linz, Austria. ^[4] MRC Laboratory of Molecular Biology, Cambridge, United Kingdom. ^[5] Department of Molecular Biology, University of Salzburg, Salzburg, Austria. Electronic address: Richard.Weiss@sbg.ac.at. ^[6]

关键词 Allergic sensitization Bet v 1 antigen processing and presentation endolysosomal degradation molecular allergology structural stability