Immunogenicity and Protective Efficacy of Brugia malayi Heavy Chain Myosin as Homologous DNA, Protein and Heterologous DNA/Protein Prime Boost Vaccine in Rodent Model.
第一作者:
Jyoti,Gupta
第一单位:
Division of Parasitology, CSIR-Central Drug Research Institute, BS 10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow-226031, India.;Academy of scientific and Innovative Research, New Delhi, India.
作者:
医学主题词
动物(Animals);马来丝虫(Brugia malayi);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞黏附(Cell Adhesion);克隆, 分子(Cloning, Molecular);细胞因子类(Cytokines);丝虫病(Filariasis);基因表达调控(Gene Expression Regulation);白细胞介素10(Interleukin-10);白细胞介素4(Interleukin-4);白细胞(Leukocytes);巨噬细胞, 腹膜(Macrophages, Peritoneal);男(雄)性(Male);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);肌球蛋白重链(Myosin Heavy Chains);活性氧(Reactive Oxygen Species);脾(Spleen);Th2细胞(Th2 Cells);疫苗, DNA(Vaccines, DNA);Vero细胞(Vero Cells)
DOI
10.1371/journal.pone.0142548
PMID
26560102
发布时间
2019-12-10
- 浏览10
PloS one
e0142548页
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