A Phase I Trial of BKM120 (Buparlisib) in Combination with Fulvestrant in Postmenopausal Women with Estrogen Receptor-Positive Metastatic Breast Cancer.

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作者： Cynthia X,Ma ^[1] ; Jingqin,Luo ^[2] ; Michael,Naughton ^[3] ; Foluso,Ademuyiwa ^[3] ; Rama,Suresh ^[3] ; Malachi,Griffith ^[4] ; Obi L,Griffith ^[5] ; Zachary L,Skidmore ^[6] ; Nicholas C,Spies ^[6] ; Avinash,Ramu ^[6] ; Lee,Trani ^[6] ; Timothy,Pluard ^[3] ; Gayathri,Nagaraj ^[7] ; Shana,Thomas ^[7] ; Zhanfang,Guo ^[7] ; Jeremy,Hoog ^[7] ; Jing,Han ^[7] ; Elaine,Mardis ^[8] ; Craig,Lockhart ^[3] ; Matthew J,Ellis ^[9]

作者单位： Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri. cma@dom.wustl.edu mjellis@bcm.edu. ^[1] Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri. ^[2] Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri. ^[3] Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri. The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri. Department of Genetics, Washington University School of Medicine, St. Louis, Missouri. ^[4] Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri. The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri. Department of Genetics, Washington University School of Medicine, St. Louis, Missouri. ^[5] The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri. ^[6] Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. ^[7] Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri. The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri. Department of Genetics, Washington University School of Medicine, St. Louis, Missouri. Division of Genomics and Bioinformatics, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. ^[8] Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas. cma@dom.wustl.edu mjellis@bcm.edu. ^[9]