Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.
第一作者:
Torsten,Lowin
第一单位:
Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine I, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93042, Regensburg, Germany. torsten.lowin@ukr.de.
作者:
主题词
老年人(Aged);动物(Animals);消炎药(Anti-Inflammatory Agents);关节炎, 类风湿(Arthritis, Rheumatoid);钙通道(Calcium Channels);细胞, 培养的(Cells, Cultured);环氧化酶2(Cyclooxygenase 2);环氧化酶2抑制剂(Cyclooxygenase 2 Inhibitors);剂量效应关系, 药物(Dose-Response Relationship, Drug);乙醇胺类(Ethanolamines);女(雌)性(Female);人类(Humans);炎症介导素类(Inflammation Mediators);男(雄)性(Male);小鼠(Mice);小鼠, 近交DBA(Mice, Inbred DBA);中年人(Middle Aged);神经组织蛋白质类(Nerve Tissue Proteins);滑膜(Synovial Membrane);TRPV阳离子通道(TRPV Cation Channels);瞬时受体电位通道(Transient Receptor Potential Channels)
DOI
10.1186/s13075-015-0845-5
PMID
26567045
发布时间
2022-03-31
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