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Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials.

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第一单位: Department of Neurology, University of Rochester, Rochester, New York.
作者: Huntington Study Group PHAROS Investigators [1] ; Kevin Michael,Biglan [2] ; Ira,Shoulson [1] ; Karl,Kieburtz [3] ; David,Oakes [1] ; Elise,Kayson [1] ; M Aileen,Shinaman [4] ; Hongwei,Zhao [5] ; Megan,Romer [6] ; Anne,Young [6] ; Steven,Hersch [6] ; Jack,Penney [7] ; Karen,Marder [8] ; Jane,Paulsen [9] ; Kimberly,Quaid [10] ; Eric,Siemers [11] ; Caroline,Tanner [12] ; William,Mallonee [13] ; Greg,Suter [13] ; Richard,Dubinsky [13] ; Carolyn,Gray [14] ; Martha,Nance [14] ; Scott,Bundlie [14] ; Dawn,Radtke [15] ; Sandra,Kostyk [15] ; Corrine,Baic [16] ; James,Caress [16] ; Francis,Walker [16] ; Victoria,Hunt [16] ; Christine,O'Neill [17] ; Sylvain,Chouinard [18] ; Stewart,Factor [18] ; Timothy,Greenamyre [18] ; Cathy,Wood-Siverio [19] ; Jody,Corey-Bloom [19] ; David,Song [19] ; Guerry,Peavy [9] ; Carol,Moskowitz [20] ; Melissa,Wesson [20] ; Ali,Samii [20] ; Thomas,Bird [21] ; Hillary,Lipe [1] ; Karen,Blindauer [1] ; Frederick,Marshall [1] ; Carol,Zimmerman [6] ; Jody,Goldstein [6] ; Diana,Rosas [22] ; Peter,Novak [22] ; John,Caviness [22] ; Charles,Adler [23] ; Amy,Duffy [23] ; Vicki,Wheelock [23] ; Teresa,Tempkin [24] ; David,Richman [25] ; Lauren,Seeberger [25] ; Roger,Albin [26] ; Kelvin L,Chou [26] ; Brad,Racette [27] ; Joel S,Perlmutter [27] ; Susan,Perlman [28] ; Yvette,Bordelon [28] ; Wayne,Martin [29] ; Marguerite,Wieler [29] ; Blair,Leavitt [29] ; Lynn,Raymond [29] ; Joji,Decolongon [30] ; Lorne,Clarke [30] ; Joseph,Jankovic [31] ; Christine,Hunter [31] ; Robert A,Hauser [32] ; Juan,Sanchez-Ramos [32] ; Sarah,Furtado [30] ; Oksana,Suchowersky [33] ; Mary Lou,Klimek [33] ; Mark,Guttman [34] ; Rustom,Sethna [34] ; Andrew,Feigin [34] ; Marie,Cox [35] ; Barbara,Shannon [35] ; Alan,Percy [36] ; Leon,Dure [37] ; Madaline,Harrison [38] ; William,Johnson [38] ; Donald,Higgins [38] ; Eric,Molho [38] ; Constance,Nickerson [39] ; Sharon,Evans [40] ; Douglas,Hobson [40] ; Carlos,Singer [41] ; Nestor,Galvez-Jimenez [41] ; Kathleen,Shannon [42] ; Cynthia,Comella [43] ; Christopher,Ross [44] ; Marie H,Saint-Hilaire [44] ; Claudia,Testa [45] ; Adam,Rosenblatt [46] ; Penelope,Hogarth [47] ; William,Weiner [48] ; Peter,Como [49] ; Rajeev,Kumar [50] ; Candace,Cotto [1] ; Julie,Stout [1] ; Alicia,Brocht [3] ; Arthur,Watts [1] ; Shirley,Eberly [9] ; Christine,Weaver [6] ; Tatiana,Foroud [6] ; James,Gusella [43] ; Marcy,MacDonald [7] ; Richard,Myers [19] ; Stanley,Fahn ; Clifford,Shults
作者单位: Department of Neurology, University of Rochester, Rochester, New York. [1] Department of Neurology, Georgetown University, Washington, DC. [2] Department of Biostatics, University of Rochester, Rochester, New York. [3] Department of Epidemiology & Biostatistics, Texas A&M, College Station. [4] Department of Statistics, Pennsylvania State University, University Park. [5] Department of Neurology, Massachusetts General Hospital, Charleston. [6] Department of Neurology, Columbia University Medical Center, New York, New York. [7] Department of Psychiatry and Neurology, University of Iowa, Iowa City. [8] Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis. [9] Lilly Corporate Center, Indianapolis, Indiana. [10] The Parkinson's Institute, Sunnyvale, California. [11] Hereditary Neurological Disease Centre, Wichita, Kansas. [12] Department of Neurology, University of Kansas Medical Center, Kansas City. [13] Department of Neurology, Hennepin County Medical Center/Minneapolis, Minneapolis, Minnesota. [14] Department of Neurology, The Ohio State University, Columbus. [15] Wake Forest University School of Medicine, Winston-Salem, North Carolina. [16] Hotel-Dieu Hospital-CHUM, Montreal, Quebec, Canada. [17] Department of Neurology, Emory University School of Medicine, Atlanta, Georgia. [18] Department of Neuroscience, University of California, San Diego, La Jolla. [19] Department of Neurology, University of Washington, Seattle21Veterans Affairs Puget Sound Health Care System, Seattle. [20] Department of Neurology, Medical College of Wisconsin, Milwaukee. [21] Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, Arizona. [22] Department of Neurology, University of California, Davis, Sacramento. [23] Idaho Elks Rehabilitation Hospital, Boise. [24] Department of Neurology, University of Michigan, Ann Arbor. [25] Department of Neurology, Washington University, St Louis, Missouri. [26] Department of Neurology, University of California Los Angeles Medical Center, Los Angeles. [27] Department of Neurology, University of Alberta, Edmonton, Alberta, Canada. [28] Department of Neurology, University of British Columbia, Vancouver, British Columbia, Canada. [29] Department of Neurology, Baylor College of Medicine, Houston, Texas. [30] Department of Neurology, University of South Florida, Tampa. [31] Department of Neurology, University of Calgary, Calgary, Alberta, Canada. [32] Centre for Addiction and Mental Health, Markham, Ontario, Canada. [33] Department of Neurology, North Shore LIJ University Hospital, Manhasset, New York. [34] Department of Neurobiology, University of Alabama at Birmingham. [35] Department of Neurology, University of Virginia, Charlottesville. [36] Department of Neurology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical Center, Stratford. [37] Department of Neurology, Albany Medical College, Albany, New York. [38] Winnipeg Clinic, Winnipeg, Manitoba, Canada. [39] Department of Neurology, University of Miami, Miami, Florida. [40] Department of Neurological Sciences, Rush University, Chicago, Illinois. [41] Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland. [42] Department of Neurology, Boston University, Boston, Massachusetts. [43] Department of Neurology, Virginia Commonwealth University, Richmond. [44] Department of Neurology, Oregon Health and Science University, Portland. [45] Department of Neurology, University of Maryland School of Medicine, Baltimore. [46] US Food and Drug Administration, Rockville, Maryland. [47] Department of Neurology, Rocky Mountain Movement Disorders Center, Denver, Colorado. [48] Department of Neurology, Institute for Neurodegenerative Disorders, New Haven, Connecticut. [49] Clinical and Cognitive Neuroscience Laboratory, Monash University, Melbourne, Australia. [50]
DOI 10.1001/jamaneurol.2015.2736
PMID 26569098
发布时间 2022-04-08
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JAMA neurology

JAMA neurology

2016年73卷1期

102-10页

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