Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials.
第一单位:
Department of Neurology, University of Rochester, Rochester, New York.
作者:
Huntington Study Group PHAROS Investigators [1]
;
Kevin Michael,Biglan [2]
;
Ira,Shoulson [1]
;
Karl,Kieburtz [3]
;
David,Oakes [1]
;
Elise,Kayson [1]
;
M Aileen,Shinaman [4]
;
Hongwei,Zhao [5]
;
Megan,Romer [6]
;
Anne,Young [6]
;
Steven,Hersch [6]
;
Jack,Penney [7]
;
Karen,Marder [8]
;
Jane,Paulsen [9]
;
Kimberly,Quaid [10]
;
Eric,Siemers [11]
;
Caroline,Tanner [12]
;
William,Mallonee [13]
;
Greg,Suter [13]
;
Richard,Dubinsky [13]
;
Carolyn,Gray [14]
;
Martha,Nance [14]
;
Scott,Bundlie [14]
;
Dawn,Radtke [15]
;
Sandra,Kostyk [15]
;
Corrine,Baic [16]
;
James,Caress [16]
;
Francis,Walker [16]
;
Victoria,Hunt [16]
;
Christine,O'Neill [17]
;
Sylvain,Chouinard [18]
;
Stewart,Factor [18]
;
Timothy,Greenamyre [18]
;
Cathy,Wood-Siverio [19]
;
Jody,Corey-Bloom [19]
;
David,Song [19]
;
Guerry,Peavy [9]
;
Carol,Moskowitz [20]
;
Melissa,Wesson [20]
;
Ali,Samii [20]
;
Thomas,Bird [21]
;
Hillary,Lipe [1]
;
Karen,Blindauer [1]
;
Frederick,Marshall [1]
;
Carol,Zimmerman [6]
;
Jody,Goldstein [6]
;
Diana,Rosas [22]
;
Peter,Novak [22]
;
John,Caviness [22]
;
Charles,Adler [23]
;
Amy,Duffy [23]
;
Vicki,Wheelock [23]
;
Teresa,Tempkin [24]
;
David,Richman [25]
;
Lauren,Seeberger [25]
;
Roger,Albin [26]
;
Kelvin L,Chou [26]
;
Brad,Racette [27]
;
Joel S,Perlmutter [27]
;
Susan,Perlman [28]
;
Yvette,Bordelon [28]
;
Wayne,Martin [29]
;
Marguerite,Wieler [29]
;
Blair,Leavitt [29]
;
Lynn,Raymond [29]
;
Joji,Decolongon [30]
;
Lorne,Clarke [30]
;
Joseph,Jankovic [31]
;
Christine,Hunter [31]
;
Robert A,Hauser [32]
;
Juan,Sanchez-Ramos [32]
;
Sarah,Furtado [30]
;
Oksana,Suchowersky [33]
;
Mary Lou,Klimek [33]
;
Mark,Guttman [34]
;
Rustom,Sethna [34]
;
Andrew,Feigin [34]
;
Marie,Cox [35]
;
Barbara,Shannon [35]
;
Alan,Percy [36]
;
Leon,Dure [37]
;
Madaline,Harrison [38]
;
William,Johnson [38]
;
Donald,Higgins [38]
;
Eric,Molho [38]
;
Constance,Nickerson [39]
;
Sharon,Evans [40]
;
Douglas,Hobson [40]
;
Carlos,Singer [41]
;
Nestor,Galvez-Jimenez [41]
;
Kathleen,Shannon [42]
;
Cynthia,Comella [43]
;
Christopher,Ross [44]
;
Marie H,Saint-Hilaire [44]
;
Claudia,Testa [45]
;
Adam,Rosenblatt [46]
;
Penelope,Hogarth [47]
;
William,Weiner [48]
;
Peter,Como [49]
;
Rajeev,Kumar [50]
;
Candace,Cotto [1]
;
Julie,Stout [1]
;
Alicia,Brocht [3]
;
Arthur,Watts [1]
;
Shirley,Eberly [9]
;
Christine,Weaver [6]
;
Tatiana,Foroud [6]
;
James,Gusella [43]
;
Marcy,MacDonald [7]
;
Richard,Myers [19]
;
Stanley,Fahn ;
Clifford,Shults
作者单位:
Department of Neurology, University of Rochester, Rochester, New York.
[1]
Department of Neurology, Georgetown University, Washington, DC.
[2]
Department of Biostatics, University of Rochester, Rochester, New York.
[3]
Department of Epidemiology & Biostatistics, Texas A&M, College Station.
[4]
Department of Statistics, Pennsylvania State University, University Park.
[5]
Department of Neurology, Massachusetts General Hospital, Charleston.
[6]
Department of Neurology, Columbia University Medical Center, New York, New York.
[7]
Department of Psychiatry and Neurology, University of Iowa, Iowa City.
[8]
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis.
[9]
Lilly Corporate Center, Indianapolis, Indiana.
[10]
The Parkinson's Institute, Sunnyvale, California.
[11]
Hereditary Neurological Disease Centre, Wichita, Kansas.
[12]
Department of Neurology, University of Kansas Medical Center, Kansas City.
[13]
Department of Neurology, Hennepin County Medical Center/Minneapolis, Minneapolis, Minnesota.
[14]
Department of Neurology, The Ohio State University, Columbus.
[15]
Wake Forest University School of Medicine, Winston-Salem, North Carolina.
[16]
Hotel-Dieu Hospital-CHUM, Montreal, Quebec, Canada.
[17]
Department of Neurology, Emory University School of Medicine, Atlanta, Georgia.
[18]
Department of Neuroscience, University of California, San Diego, La Jolla.
[19]
Department of Neurology, University of Washington, Seattle21Veterans Affairs Puget Sound Health Care System, Seattle.
[20]
Department of Neurology, Medical College of Wisconsin, Milwaukee.
[21]
Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, Arizona.
[22]
Department of Neurology, University of California, Davis, Sacramento.
[23]
Idaho Elks Rehabilitation Hospital, Boise.
[24]
Department of Neurology, University of Michigan, Ann Arbor.
[25]
Department of Neurology, Washington University, St Louis, Missouri.
[26]
Department of Neurology, University of California Los Angeles Medical Center, Los Angeles.
[27]
Department of Neurology, University of Alberta, Edmonton, Alberta, Canada.
[28]
Department of Neurology, University of British Columbia, Vancouver, British Columbia, Canada.
[29]
Department of Neurology, Baylor College of Medicine, Houston, Texas.
[30]
Department of Neurology, University of South Florida, Tampa.
[31]
Department of Neurology, University of Calgary, Calgary, Alberta, Canada.
[32]
Centre for Addiction and Mental Health, Markham, Ontario, Canada.
[33]
Department of Neurology, North Shore LIJ University Hospital, Manhasset, New York.
[34]
Department of Neurobiology, University of Alabama at Birmingham.
[35]
Department of Neurology, University of Virginia, Charlottesville.
[36]
Department of Neurology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical Center, Stratford.
[37]
Department of Neurology, Albany Medical College, Albany, New York.
[38]
Winnipeg Clinic, Winnipeg, Manitoba, Canada.
[39]
Department of Neurology, University of Miami, Miami, Florida.
[40]
Department of Neurological Sciences, Rush University, Chicago, Illinois.
[41]
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland.
[42]
Department of Neurology, Boston University, Boston, Massachusetts.
[43]
Department of Neurology, Virginia Commonwealth University, Richmond.
[44]
Department of Neurology, Oregon Health and Science University, Portland.
[45]
Department of Neurology, University of Maryland School of Medicine, Baltimore.
[46]
US Food and Drug Administration, Rockville, Maryland.
[47]
Department of Neurology, Rocky Mountain Movement Disorders Center, Denver, Colorado.
[48]
Department of Neurology, Institute for Neurodegenerative Disorders, New Haven, Connecticut.
[49]
Clinical and Cognitive Neuroscience Laboratory, Monash University, Melbourne, Australia.
[50]
医学主题词
成年人(Adult);队列研究(Cohort Studies);女(雌)性(Female);遗传关联研究(Genetic Association Studies);人类(Humans);杭廷顿病(Huntington Disease);纵向研究(Longitudinal Studies);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);前瞻性研究(Prospective Studies);随机对照试验(主题)(Randomized Controlled Trials as Topic);单盲法(Single-Blind Method);三核苷酸重复扩增(Trinucleotide Repeat Expansion)
DOI
10.1001/jamaneurol.2015.2736
PMID
26569098
发布时间
2022-04-08
- 浏览17
JAMA neurology
JAMA neurology
2016年73卷1期
102-10页
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