Plastin 3 is upregulated in iPSC-derived motoneurons from asymptomatic SMN1-deleted individuals.

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第一作者： Ludwig,Heesen

第一单位： Institute of Human Genetics, Institute of Genetics and Center for Molecular Medicine Cologne, University of Cologne, Kerpener Str. 34, 50931, Cologne, Germany.;Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany.

作者： Ludwig,Heesen ^[1] ; Michael,Peitz ^[2] ; Laura,Torres-Benito ^[3] ; Irmgard,Hölker ^[3] ; Kristina,Hupperich ^[4] ; Kristina,Dobrindt ^[4] ; Johannes,Jungverdorben ^[2] ; Swetlana,Ritzenhofen ^[4] ; Beatrice,Weykopf ^[2] ; Daniela,Eckert ^[4] ; Seyyed Mohsen,Hosseini-Barkooie ^[3] ; Markus,Storbeck ^[3] ; Noemi,Fusaki ^[5] ; Renata,Lonigro ^[6] ; Raoul,Heller ^[3] ; Min Jeong,Kye ^[3] ; Oliver,Brüstle ^[7] ; Brunhilde,Wirth ^[8]

作者单位： Institute of Human Genetics, Institute of Genetics and Center for Molecular Medicine Cologne, University of Cologne, Kerpener Str. 34, 50931, Cologne, Germany.;Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany. ^[1] Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany.;DZNE, German Center for Neurodegenerative Diseases, Bonn, Germany. ^[2] Institute of Human Genetics, Institute of Genetics and Center for Molecular Medicine Cologne, University of Cologne, Kerpener Str. 34, 50931, Cologne, Germany. ^[3] Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany. ^[4] Keio University School of Medicine and JST PRESTO, Tokyo, Japan. ^[5] Department of Biological and Medical Sciences, University of Udine, Udine, Italy.;Institute of Clinical Pathology, A. O. U, Udine, Italy. ^[6] Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany. brustle@uni-bonn.de.;DZNE, German Center for Neurodegenerative Diseases, Bonn, Germany. brustle@uni-bonn.de. ^[7] Institute of Human Genetics, Institute of Genetics and Center for Molecular Medicine Cologne, University of Cologne, Kerpener Str. 34, 50931, Cologne, Germany. brunhilde.wirth@uk-koeln.de. ^[8]

关键词 F-actin dynamics Gene expression Gene modifier Growth cones Sendai virus