换一批
第一作者：
Lili,Ding
第一单位：
Shanghai Key Laboratory of Complex Prescriptions and MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China ; Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.
作者：
关键词
6-ECDCA, 6α-ethyl-chenodeoxycholic acidAF2, activation domainANGTPL3, angiopoietin-like protein 3AOM, azoxymethaneAP-1, activator protein-1ASBT, apical sodium-dependent bile salt transporterApo, apolipoproteinBAAT, bile acid-CoA amino acid N-acetyltransferaseBACS, bile acid-CoA synthetaseBAs, bile acidsBMI, body mass indexBSEP, bile salt export pumpBile acidsCA, cholic acidCD, Crohn?s diseaseCDCA, chenodeoxycholic acidCREB, cAMP regulatory element-binding proteinCYP7A1, cholesterol 7α-hydroxylaseColorectal cancerDBD, DNA binding domainDCA, deoxycholic acidDSS, dextrane sodium sulfateERK, extracellular signal-regulated kinaseFABP6, fatty acid-binding protein subclass 6FFAs, free fatty acidsFGF19, fibroblast growth factor 19FGFR4, fibroblast growth factor receptor 4FXR, farnesoid X receptorFXRE, farnesoid X receptor response elementFarnesoid X receptorG6Pase, glucose-6-phosphataseGLP-1, glucagon-like peptide 1GLUT2, glucose transporter type 2GPBAR, G protein-coupled BA receptorGPCRs, G protein-coupled receptorsGSK3, glycogen synthase kinase 3Gastrointestinal tractHDL-C, high density lipoprotein cholesterolHNF4α, hepatic nuclear factor 4αI-BABP, intestinal bile acid-binding proteinIBD, inflammatory bowel diseaseIL-1, interleukin 1Inflammatory bowel diseaseKLF11, Krüppel-like factor 11KRAS, Kirsten rat sarcoma viral oncogene homologLBD, ligand binding domainLCA, lithocholic acidLPL, lipoprotein lipaseLRH-1, liver receptor homolog-1MCA, muricholicacidMRP2, multidrug resistance-associated protein 2NF-κB, nuclear factor-kappa BNOD, non-obese diabeticNRs, nuclear receptorsOSTα, organic solute transporter alphaOSTβ, organic solute transporter betaPEPCK, phosphoenol pyruvate carboxykinasePGC-1α, peroxisome proliferators-activated receptor γ coactivator protein-1αSHP, small heterodimer partnerSREBP-1c, sterol regulatory element-binding protein 1cSTAT3, signal transducers and activators of transcription 3T2D, type 2 diabetesTLCA, taurolithocholic acidTNBS, trinitrobenzensulfonic acidTNFα, tumor necrosis factors αType 2 diabetesUC, ulcerative colitisUDCA, ursodeoxycholic acidVSG, vertical sleeve gastrectomydb/db, diabetic mice
DOI
10.1016/j.apsb.2015.01.004
PMID
26579439
发布时间
2022-04-09
- 浏览53
Acta pharmaceutica Sinica. B
2015年5卷2期
135-44页
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