Study on pharmacokinetics and tissue distribution of the isocorydine derivative (AICD) in rats by HPLC-DAD method.
第一作者:
Yali,Chen
第一单位:
Institute of Medicinal Chemistry, School of Pharmacy, Lanzhou University, Lanzhou 730000, China ; Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
作者:
关键词
8-Acetamino-isocorydineAICD, 8-acetamino-isocorydineAUC, area under concentration-time curveAlkaloidsF, absolute bioavailabilityHPLC-DAD, high-performance liquid chromatography with diode-array detectionHPLC-UV, high-performance liquid chromatography coupled with ultraviolet detectionHigh-performance liquid chromatography with diode-array detectionICD, isocorydineIS, internal standardLC-ESI-MS/MS, high-performance liquid chromatography–electrospray ionization–tandem mass spectrometryLLE, liquid-liquid extractionLLOQ, lower limit of quantificationLOD, limit of detectionPharmacokineticsQC, quality controlRE, relative errorRP, reverse phaseRSD, relative standard deviationSD, standard deviation.Tissue distribution
DOI
10.1016/j.apsb.2015.03.012
PMID
26579452
发布时间
2020-09-30
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Acta pharmaceutica Sinica. B
2015年5卷3期
238-45页
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