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首页> Journal of virology> Dysregulation of Toll-Like Receptor 7 Compromises Innate and Adaptive T Cell Responses and Host Resistance to an Attenuated West Nile Virus Infection in Old Mice.

Dysregulation of Toll-Like Receptor 7 Compromises Innate and Adaptive T Cell Responses and Host Resistance to an Attenuated West Nile Virus Infection in Old Mice.

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作者： Guorui,Xie ^[1] ; Huanle,Luo ^[1] ; Lan,Pang ^[1] ; Bi-Hung,Peng ^[2] ; Evandro,Winkelmann ^[1] ; Brenna,McGruder ^[1] ; Joseph,Hesse ^[1] ; Melissa,Whiteman ^[2] ; Gerald,Campbell ^[2] ; Gregg N,Milligan ^[3] ; Yingzi,Cong ^[4] ; Alan D,Barrett ^[4] ; Tian,Wang ^[5]

作者单位： Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, Texas, USA. ^[1] Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA. ^[2] Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA. ^[3] Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, Texas, USA Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, USA. ^[4] Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, Texas, USA Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, USA ti1wang@utmb.edu. ^[5]

主题词适应性免疫(Adaptive Immunity);年龄因素(Age Factors);动物(Animals);组织细胞化学(Histocytochemistry);免疫, 先天(Immunity, Innate);小鼠, 近交C57BL(Mice, Inbred C57BL);存活率分析(Survival Analysis);T淋巴细胞(T-Lymphocytes);Toll样受体7(Toll-Like Receptor 7);病毒载量(Viral Load);西尼罗热(West Nile Fever);西尼罗病毒(West Nile virus)

DOI 10.1128/JVI.02488-15

PMID 26581984

发布时间 2020-12-15

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Journal of virology

Journal of virology

2016年90卷3期

1333-44页

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Journal of virology

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Journal of virology

2016年90卷3期

1333-44页

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