GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands.

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作者： Yangmi,Lim ^[1] ; Jiho,Yoo ^[2] ; Min-Soo,Kim ^[1] ; Minkyu,Hur ^[3] ; Eun Hee,Lee ^[1] ; Hyung-Suk,Hur ^[1] ; Jae-Chul,Lee ^[1] ; Shi-Nai,Lee ^[1] ; Tae Wook,Park ^[1] ; Kyuhyun,Lee ^[1] ; Ki Hwan,Chang ^[1] ; Kuglae,Kim ^[2] ; YingJin,Kang ^[2] ; Kwang-Won,Hong ^[1] ; Se-Ho,Kim ^[4] ; Yeon-Gil,Kim ^[5] ; Yeup,Yoon ^[6] ; Do-Hyun,Nam ^[7] ; Heekyoung,Yang ^[8] ; Dong Geon,Kim ^[9] ; Hyun-Soo,Cho ^[10] ; Jonghwa,Won ^[11]

作者单位： MOGAM Biotechnology Institute, Yongin, Gyeonggi-do, Republic of Korea. ^[1] Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea. ^[2] MOGAM Biotechnology Institute, Yongin, Gyeonggi-do, Republic of Korea. Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul, Republic of Korea. ^[3] University-Industry Cooperation Foundation, and Department of Systems Immunology, College of Biomedical Science, Kangwon National University, Chuncheon, Kangwon-Do, Republic of Korea. ^[4] Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea. ^[5] Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Republic of Korea. Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Republic of Korea. Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea. ^[6] Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Republic of Korea. Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Republic of Korea. Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea. Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Republic of Korea. ^[7] Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Republic of Korea. Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Republic of Korea. Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Republic of Korea. ^[8] Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Republic of Korea. Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea. ^[9] Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea. agnes@mogam.re.kr hscho8@yonsei.ac.kr. ^[10] MOGAM Biotechnology Institute, Yongin, Gyeonggi-do, Republic of Korea. agnes@mogam.re.kr hscho8@yonsei.ac.kr. ^[11]