Haplosufficiency of PAX3 for melanoma development in Tyr: NRASQ61K; Cdkn2a-/- mice allows identification and sorting of melanoma cells using a Pax3GFP reporter allele.
作者:
主题词
等位基因(Alleles);氨基酸取代(Amino Acid Substitution);动物(Animals);细胞分离(Cell Separation);细胞转化, 肿瘤(Cell Transformation, Neoplastic);细胞, 培养的(Cells, Cultured);女(雌)性(Female);基因, 报告(Genes, Reporter);基因, p16(Genes, p16);基因, ras(Genes, ras);绿色荧光蛋白质类(Green Fluorescent Proteins);单倍剂量不足(Haploinsufficiency);黑色素瘤(Melanoma);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);一元酚单氧酶(Monophenol Monooxygenase);成对盒转录因子类(Paired Box Transcription Factors);皮肤肿瘤(Skin Neoplasms)
DOI
10.1097/CMR.0000000000000212
PMID
26587692
发布时间
2017-01-03
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Melanoma research
12-20页
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