首页> Annals of oncology : official journal of the European Society for Medical Oncology> Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing?

Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing?

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第一作者： S,Postel-Vinay

第一单位： Drug Development Unit, Gustave Roussy Department of Medical Oncology, Faculté de medicine Paris-Sud XI, Kremlin-Bicêtre sophie.postel-vinay@gustaveroussy.fr.

作者： S,Postel-Vinay ^[1] ; Y,Boursin ^[2] ; C,Massard ^[3] ; A,Hollebecque ^[3] ; E,Ileana ^[4] ; M,Chiron ^[5] ; J,Jung ^[6] ; J S,Lee ^[6] ; Z,Balogh ^[7] ; J,Adam ^[7] ; P,Vielh ^[7] ; E,Angevin ^[4] ; L,Lacroix ^[7] ; J-C,Soria ^[3]

作者单位： Drug Development Unit, Gustave Roussy Department of Medical Oncology, Faculté de medicine Paris-Sud XI, Kremlin-Bicêtre sophie.postel-vinay@gustaveroussy.fr. ^[1] Bioinformatic platform, AMMICA, INSERM US23/CNRS UMS3655, Gustave Roussy. ^[2] Drug Development Unit, Gustave Roussy Department of Medical Oncology, Faculté de medicine Paris-Sud XI, Kremlin-Bicêtre. ^[3] Drug Development Unit, Gustave Roussy. ^[4] Sanofi, Translational Medicine, Oncology Unit, Vitry-sur-Seine, France. ^[5] Sanofi, Translational Medicine, Oncology Unit, Cambridge, USA. ^[6] Laboratory of Translational Research and Biological Resource Center, AMMICA, INSERM US23/CNRS UMS3655 Department of Medical Biology and Pathology, Gustave Roussy, France. ^[7]

关键词 array comparative genomic hybridization flat profile precision medicine targeted gene panel sequencing whole exome sequencing