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首页> Clinical cancer research : an official journal of the American Association for Cancer Research> XPO1 Inhibition Enhances Radiation Response in Preclinical Models of Rectal Cancer.

XPO1 Inhibition Enhances Radiation Response in Preclinical Models of Rectal Cancer.

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第一作者： Isabel,Ferreiro-Neira

第一单位： Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. jcusack@partners.org isabel.ferreironeira@gmail.com.

作者： Isabel,Ferreiro-Neira ^[1] ; Nancy E,Torres ^[2] ; Lukas F,Liesenfeld ^[2] ; Carlos H F,Chan ^[2] ; Tristan,Penson ^[2] ; Yosef,Landesman ^[3] ; William,Senapedis ^[3] ; Sharon,Shacham ^[3] ; Theodore S,Hong ^[4] ; James C,Cusack ^[1]

作者单位： Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. jcusack@partners.org isabel.ferreironeira@gmail.com. ^[1] Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. ^[2] Karyopharm Therapeutics, Natick, Massachusetts. ^[3] Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts. Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts. ^[4]

主题词动物(Animals);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);综合疗法(Combined Modality Therapy);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);肼类(Hydrazines);凋亡抑制蛋白质类(Inhibitor of Apoptosis Proteins);核胞浆转运蛋白类(Karyopherins);小鼠(Mice);辐射(Radiation);辐射耐受性(Radiation Tolerance);辐射增敏药(Radiation-Sensitizing Agents);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);直肠肿瘤(Rectal Neoplasms);三唑类(Triazoles);肿瘤负荷(Tumor Burden);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1158/1078-0432.CCR-15-0978

PMID 26603256

发布时间 2023-12-13

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Clinical cancer research : an official journal of the American Association for Cancer Research

Clinical cancer research

2016年22卷7期

1663-73页

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