Trioxolane-Mediated Delivery of Mefloquine Limits Brain Exposure in a Mouse Model of Malaria.

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第一作者： Erica M W,Lauterwasser

第一单位： Department of Pharmaceutical Chemistry and Department of Medicine, University of California San Francisco , 1700 Fourth Street, San Francisco, California 94158, United States.

作者： Erica M W,Lauterwasser ^[1] ; Shaun D,Fontaine ^[1] ; Hao,Li ^[2] ; Jiri,Gut ^[1] ; Kasiram,Katneni ^[3] ; Susan A,Charman ^[3] ; Philip J,Rosenthal ^[1] ; Matthew,Bogyo ^[2] ; Adam R,Renslo ^[1]

作者单位： Department of Pharmaceutical Chemistry and Department of Medicine, University of California San Francisco , 1700 Fourth Street, San Francisco, California 94158, United States. ^[1] Departments of Pathology and Microbiology and Immunology, Stanford School of Medicine , 300 Pasteur Drive, Stanford, California 94305, United States. ^[2] Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Monash University , Parkville, VIC 3052, Australia. ^[3]

关键词 antimalarial drug delivery mefloquine trioxolane

DOI 10.1021/acsmedchemlett.5b00296

PMID 26617969

发布时间 2020-09-29

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ACS medicinal chemistry letters

2015年6卷11期

1145-9页

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Trioxolane-Mediated Delivery of Mefloquine Limits Brain Exposure in a Mouse Model of Malaria.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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Trioxolane-Mediated Delivery of Mefloquine Limits Brain Exposure in a Mouse Model of Malaria.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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