换一批
换一批Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.
第一作者：
Timothy H T,Cheng
第一单位：
Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
作者：
Timothy H T,Cheng [1]
;
Deborah,Thompson [2]
;
Jodie,Painter [3]
;
Tracy,O'Mara [3]
;
Maggie,Gorman [1]
;
Lynn,Martin [1]
;
Claire,Palles [1]
;
Angela,Jones [1]
;
Daniel D,Buchanan [4]
;
Aung Ko,Win [5]
;
John,Hopper [5]
;
Mark,Jenkins [5]
;
Noralane M,Lindor [6]
;
Polly A,Newcomb [7]
;
Steve,Gallinger [8]
;
David,Conti [9]
;
Fred,Schumacher [9]
;
Graham,Casey [9]
;
Graham G,Giles [10]
;
Paul,Pharoah [11]
;
Julian,Peto [12]
;
Angela,Cox [13]
;
Anthony,Swerdlow [14]
;
Fergus,Couch [15]
;
Julie M,Cunningham [16]
;
Ellen L,Goode [17]
;
Stacey J,Winham [17]
;
Diether,Lambrechts [18]
;
Peter,Fasching [19]
;
Barbara,Burwinkel [20]
;
Hermann,Brenner [21]
;
Hiltrud,Brauch [21]
;
Jenny,Chang-Claude [22]
;
Helga B,Salvesen [23]
;
Vessela,Kristensen [24]
;
Hatef,Darabi [25]
;
Jingmei,Li [25]
;
Tao,Liu [25]
;
Annika,Lindblom [25]
;
Per,Hall [26]
;
Magdalena Echeverry,de Polanco [27]
;
Monica,Sans [28]
;
Angel,Carracedo [29]
;
Sergi,Castellvi-Bel [30]
;
Augusto,Rojas-Martinez [31]
;
Samuel,Aguiar Jnr [32]
;
Manuel R,Teixeira [33]
;
Alison M,Dunning [34]
;
Joe,Dennis [2]
;
Geoffrey,Otton [35]
;
Tony,Proietto [35]
;
Elizabeth,Holliday [36]
;
John,Attia [36]
;
Katie,Ashton [36]
;
Rodney J,Scott [36]
;
Mark,McEvoy [37]
;
Sean C,Dowdy [38]
;
Brooke L,Fridley [39]
;
Henrica M J,Werner [40]
;
Jone,Trovik [40]
;
Tormund S,Njolstad [40]
;
Emma,Tham [25]
;
Miriam,Mints [41]
;
Ingo,Runnebaum [42]
;
Peter,Hillemanns [43]
;
Thilo,Dörk [44]
;
Frederic,Amant [45]
;
Stefanie,Schrauwen [18]
;
Alexander,Hein [46]
;
Matthias W,Beckmann [46]
;
Arif,Ekici [47]
;
Kamila,Czene [26]
;
Alfons,Meindl [48]
;
Manjeet K,Bolla [2]
;
Kyriaki,Michailidou [2]
;
Jonathan P,Tyrer [34]
;
Qin,Wang [2]
;
Shahana,Ahmed [34]
;
Catherine S,Healey [34]
;
Mitul,Shah [34]
;
Daniela,Annibali [49]
;
Jeroen,Depreeuw [49]
;
Nada A,Al-Tassan [50]
;
Rebecca,Harris [51]
;
Brian F,Meyer [50]
;
Nicola,Whiffin [52]
;
Fay J,Hosking [52]
;
Ben,Kinnersley [52]
;
Susan M,Farrington [53]
;
Maria,Timofeeva [53]
;
Albert,Tenesa [54]
;
Harry,Campbell [55]
;
Robert W,Haile [56]
;
Shirley,Hodgson [57]
;
Luis,Carvajal-Carmona [58]
;
Jeremy P,Cheadle [51]
;
Douglas,Easton [11]
;
Malcolm,Dunlop [53]
;
Richard,Houlston [52]
;
Amanda,Spurdle [3]
;
Ian,Tomlinson [59]
作者单位：
Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
[1]
Centre for Cancer Genetic Epidemiology, Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
[2]
The Molecular Cancer Epidemiology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia.
[3]
Oncogenomics Group, Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Victoria, Australia.;Centre for Epidemiology and Biostatistics, The University of Melbourne, Victoria, Australia.
[4]
Centre for Epidemiology and Biostatistics, The University of Melbourne, Victoria, Australia.
[5]
Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ, USA.
[6]
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
[7]
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
[8]
Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
[9]
Centre for Epidemiology and Biostatistics, The University of Melbourne, Victoria, Australia.;Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia.;Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
[10]
Centre for Cancer Genetic Epidemiology, Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.;Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
[11]
London School of Hygiene and Tropical Medicine, London, UK.
[12]
Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK.
[13]
Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK and 17 Division of Breast Cancer Research, Institute of Cancer Research, London, UK.
[14]
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.;Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
[15]
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
[16]
Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
[17]
Department of Oncology, KU Leuven, Belgium.
[18]
University of California at Los Angeles, Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine, Los Angeles, CA, USA.;Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
[19]
Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.;Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology Stuttgart, University of Tuebingen, Germany.
[20]
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology Stuttgart, University of Tuebingen, Germany.;Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
[21]
Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
[22]
Department of Clinical Science, Center for Cancer Biomarkers, University of Bergen, Norway.
[23]
Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway; The K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; Department of Clinical Molecular Oncology, Division of Medicine, Akershus University Hospital, Ahus, Norway.
[24]
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
[25]
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
[26]
Grupo de investigación Citogenética, Filogenia y Evolución de Poblaciones, Universidad del Tolima, Ibagué, Tolima, Colombia.
[27]
Departamento de Antropologia Biologica, Facultad de Humanidades, UDELAR, Magallanes 1577, CP 11200, Montevideo, Uruguay.
[28]
Universidade de Santiago de Compostel, R/ San Francisco s/n 15782, Santiago de Compostela, Spain.
[29]
Genetic Predisposition to Colorectal Cancer Group, Gastrointestinal &Pancreatic Oncology Team, IDIBAPS/CIBERehd/Hospital Clínic, Centre Esther Koplowitz (CEK), Rosselló 153 planta 4, 08036 Barcelona, Spain.
[30]
Universidad Autónoma De Nuevo León, Pedro de Alba s/n, San Nicolás de Los Garza, Nuevo León, Mexico.
[31]
Hospital A.C. Camargo, São Paulo, Brazil.
[32]
Department of Genetics and IPO-Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal, and Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal.
[33]
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
[34]
School of Medicine and Public Health, University of Newcastle, NSW, Australia.
[35]
Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia.
[36]
Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, NSW, Australia.
[37]
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, MN, USA.
[38]
Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.
[39]
Centre for Cancer Biomarkers, Department of Clinical Science, The University of Bergen, Norway.
[40]
Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
[41]
Department of Gynaecology, Jena University Hospital - Friedrich Schiller University, Jena, Germany.
[42]
Hannover Medical School, Clinics of Gynaecology and Obstetrics, Hannover, Germany.
[43]
Hannover Medical School, Gynaecology Research Unit, Hannover, Germany.
[44]
Division of Gynaecological Oncology, University Hospital Leuven, Leuven, Belgium.
[45]
Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
[46]
Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
[47]
Department of Obstetrics and Gynecology, Division of Tumor Genetics, Technical University of Munich, Munich, Germany.
[48]
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals, KU Leuven, University of Leuven, 3000, Belgium.
[49]
Department of Genetics, King Faisal Specialist Hospital and Research Center, P.O.Box 3354, Riyadh11211, Saudi Arabia.
[50]
Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.
[51]
Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK.
[52]
Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit, Western General Hospital Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.
[53]
The Roslin Institute, University of Edinburgh, Easter Bush, Roslin, EH25 9RG, UK.
[54]
Centre for Population Health Sciences, University of Edinburgh, Edinburgh, EH8 9AG, UK.
[55]
Stanford Cancer Institute, Lorry Lokey Building/SIM 1, 265 Campus Drive, Ste G2103, Stanford, CA 94305-5456, USA.
[56]
Department of Cancer Genetics, St. George's University of London, London SW17 0RE, UK.
[57]
Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, USA.
[58]
Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.;Oxford NIHR Comprehensive Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.
[59]
主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);等位基因(Alleles);结直肠肿瘤(Colorectal Neoplasms);子宫内膜肿瘤(Endometrial Neoplasms);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);男(雄)性(Male);肿瘤蛋白质类(Neoplasm Proteins);多态现象, 遗传(Polymorphism, Genetic);蛋白质类(Proteins);阻遏蛋白质类(Repressor Proteins)
DOI
10.1038/srep17369
PMID
26621817
发布时间
2024-02-10
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