JNK signaling pathway is involved in piperlongumine-mediated apoptosis in human colorectal cancer HCT116 cells.

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作者： Wen,Li ^[1] ; Chuangyu,Wen ^[2] ; Haiyan,Bai ^[3] ; Xiaoyan,Wang ^[2] ; Xiaoli,Zhang ^[4] ; Lanlan,Huang ^[2] ; Xiangling,Yang ^[2] ; Aikichi,Iwamoto ^[5] ; Huanliang,Liu ^[2]

作者单位： Guangdong Institute of Gastroenterology and The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, P.R. China ; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Sun Yat-sen University, Guangzhou, Guangdong 510655, P.R. China ; Institute of Human Virology, Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China ; Guangdong Provincial Key Laboratory of Allergy and Immunology, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China. ^[1] Guangdong Institute of Gastroenterology and The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, P.R. China ; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Sun Yat-sen University, Guangzhou, Guangdong 510655, P.R. China ; Institute of Human Virology, Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China. ^[2] State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510080, P.R. China. ^[3] Guangdong Institute of Gastroenterology and The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, P.R. China. ^[4] Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan. ^[5]

关键词 SP600125 apoptosis c-Jun NH2-terminal kinases colorectal cancer phosphorylation piperlongumine

DOI 10.3892/ol.2015.3371

PMID 26622558

发布时间 2020-09-29

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