Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs.
第一作者:
Vanesa,Nogales
第一单位:
Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
作者:
主题词
抗肿瘤药(Antineoplastic Agents);卡铂(Carboplatin);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系, 肿瘤(Cell Line, Tumor);顺铂(Cisplatin);CpG岛(CpG Islands);DEAD-box RNA解旋酶类(DEAD-box RNA Helicases);DNA(DNA);DNA甲基化(DNA Methylation);抗药性, 肿瘤(Drug Resistance, Neoplasm);后成说, 遗传(Epigenesis, Genetic);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HCT116细胞(HCT116 Cells);HEK293细胞(HEK293 Cells);人类(Humans);肺肿瘤(Lung Neoplasms);男(雄)性(Male);中年人(Middle Aged);肿瘤蛋白质类(Neoplasm Proteins);核蛋白质类(Nuclear Proteins);卵巢肿瘤(Ovarian Neoplasms);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering)
DOI
10.18632/oncotarget.6413
PMID
26625211
发布时间
2025-05-29
- 浏览67
Oncotarget
3084-97页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



