Equine grass sickness, but not botulism, causes autonomic and enteric neurodegeneration and increases soluble N-ethylmaleimide-sensitive factor attachment receptor protein expression within neuronal perikarya.

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第一作者： B C,McGorum

第一单位： Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Roslin, UK. bruce.mcgorum@ed.ac.uk.

作者： B C,McGorum ^[1] ; S,Scholes ^[2] ; E M,Milne ^[3] ; S L,Eaton ^[3] ; T M,Wishart ^[4] ; I R,Poxton ^[5] ; S,Moss ^[3] ; U,Wernery ^[6] ; T,Davey ^[7] ; J B,Harris ^[8] ; R S,Pirie ^[3]

作者单位： Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Roslin, UK. bruce.mcgorum@ed.ac.uk. ^[1] SAC Consulting Veterinary Services, Penicuik, Midlothian, UK. ^[2] Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Roslin, UK. ^[3] Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Roslin, UK.;Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Midlothian, UK. ^[4] Edinburgh Infectious Diseases, University of Edinburgh, Midlothian, UK. ^[5] Central Veterinary Research Laboratory, Dubai, United Arab Emirates. ^[6] Electron Microscopy Research Services, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. ^[7] Medical Toxicology Centre and Institute of Neuroscience, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. ^[8]

关键词 SNAP-25 SNARE proteins botulism grass sickness horse synaptobrevin syntaxin