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首页> Leukemia> Human NUP98-IQCG fusion protein induces acute myelomonocytic leukemia in mice by dysregulating the Hox/Pbx3 pathway.

Human NUP98-IQCG fusion protein induces acute myelomonocytic leukemia in mice by dysregulating the Hox/Pbx3 pathway.

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第一作者： M M,Pan

第一单位： State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University (SJTU) School of Medicine, Collaborative Innovation Center of Systems Biomedicine, SJTU, Shanghai, China.

作者： M M,Pan ^[1] ; Q Y,Zhang ^[2] ; Y Y,Wang ^[1] ; P,Liu ^[1] ; R B,Ren ^[1] ; J Y,Huang ^[1] ; L T,Chen ^[1] ; X D,Xi ^[1] ; Z,Chen ^[2] ; S J,Chen ^[2]

作者单位： State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University (SJTU) School of Medicine, Collaborative Innovation Center of Systems Biomedicine, SJTU, Shanghai, China. ^[1] State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University (SJTU) School of Medicine, Collaborative Innovation Center of Systems Biomedicine, SJTU, Shanghai, China.;Institute of Health Sciences, Shanghai Institutes for Biological Sciences and Graduate School, Chinese Academy of Sciences and (SJTU) School of Medicine, Shanghai, China. ^[2]

主题词动物(Animals);钙调蛋白结合蛋白质类(Calmodulin-Binding Proteins);细胞转化, 肿瘤(Cell Transformation, Neoplastic);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);白血病, 粒-单核细胞, 急性(Leukemia, Myelomonocytic, Acute);小鼠(Mice);核孔复合蛋白质类(Nuclear Pore Complex Proteins);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);原癌基因蛋白质类(Proto-Oncogene Proteins)

DOI 10.1038/leu.2015.347

PMID 26675333

发布时间 2018-11-13

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Leukemia

Leukemia

2016年30卷7期

1590-3页

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