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首页> Cancer research> Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer.

Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer.

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作者： Fernando,Concha-Benavente ^[1] ; Raghvendra M,Srivastava ^[2] ; Sumita,Trivedi ^[2] ; Yu,Lei ^[3] ; Uma,Chandran ^[4] ; Raja R,Seethala ^[5] ; Gordon J,Freeman ^[6] ; Robert L,Ferris ^[7]

作者单位： Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania. ^[1] Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania. ^[2] Department of Periodontics and Oral Medicine, School of Dentistry and Department of Otolaryngology-Head and Neck Surgery, School of Medicine. University of Michigan, Ann Arbor, Michigan. ^[3] Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania. ^[4] Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania. ^[5] Department of Medical Oncology, Harvard Medical School, Dana Farber Cancer Institute, Boston, Massachusetts. ^[6] Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania. Cancer Immunology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. ferrisrl@upmc.edu. ^[7]

主题词细胞系, 肿瘤(Cell Line, Tumor);表皮生长因子(Epidermal Growth Factor);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);干扰素γ(Interferon-gamma);Janus激酶2(Janus Kinase 2);杀伤细胞, 天然(Killer Cells, Natural);乳头状瘤病毒科(Papillomaviridae);STAT1转录因子(STAT1 Transcription Factor)

DOI 10.1158/0008-5472.CAN-15-2001

PMID 26676749

发布时间 2022-03-16

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2016年76卷5期

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