Deoxypodophyllotoxin triggers parthanatos in glioma cells via induction of excessive ROS.

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作者： Diandong,Ma ^[1] ; Bin,Lu ^[1] ; Chao,Feng ^[2] ; Chen,Wang ^[1] ; Yubo,Wang ^[2] ; Tianfei,Luo ^[3] ; Jiachun,Feng ^[3] ; Hongyao,Jia ^[4] ; Guangfan,Chi ^[5] ; Yinan,Luo ^[2] ; Pengfei,Ge ^[6]

作者单位： Department of Neurosurgery, First Hospital of Jilin University, Changchun 130021, China; Research Center of Neuroscience, First Hospital of Jilin University, Changchun 130021, China. ^[1] Department of Neurosurgery, First Hospital of Jilin University, Changchun 130021, China. ^[2] Research Center of Neuroscience, First Hospital of Jilin University, Changchun 130021, China; Department of Neurology, First Hospital of Jilin University, Changchun 130021, China. ^[3] Department of Breast Surgery, First Hospital of Jilin University, Changchun 130021, China. ^[4] Key Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun 130021, China. ^[5] Department of Neurosurgery, First Hospital of Jilin University, Changchun 130021, China; Research Center of Neuroscience, First Hospital of Jilin University, Changchun 130021, China. Electronic address: gepf@jlu.edu.cn. ^[6]

关键词 Deoxypodophyllotoxin Glioma PARP-1 Parthanatos ROS