1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells.
作者:
主题词
AMP活化蛋白激酶类(AMP-Activated Protein Kinases);动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞系(Cell Line);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);二氢吡啶类(Dihydropyridines);酶激活(Enzyme Activation);人类(Humans);男(雄)性(Male);小鼠(Mice);线粒体(Mitochondria);肿瘤(Neoplasms);信号传导(Signal Transduction);抗衰老酶1(Sirtuin 1);皮肤(Skin);伤口愈合(Wound Healing)
DOI
10.1021/acs.jmedchem.5b01117
PMID
26689352
发布时间
2022-04-09
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Journal of medicinal chemistry
1471-91页
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