The mannose receptor negatively modulates the Toll-like receptor 4-aryl hydrocarbon receptor-indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization.

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作者： Fabián,Salazar ^[1] ; Laurence,Hall ^[1] ; Ola H,Negm ^[2] ; Dennis,Awuah ^[1] ; Patrick J,Tighe ^[1] ; Farouk,Shakib ^[1] ; Amir M,Ghaemmaghami ^[3]

作者单位： Division of Immunology, School of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom. ^[1] Division of Immunology, School of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom; Medical Microbiology and Immunology Department, Mansoura University, Mansoura, Egypt. ^[2] Division of Immunology, School of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom. Electronic address: amg@nottingham.ac.uk. ^[3]

关键词 C-type lectin receptor Dendritic cells T(H)2 Toll-like receptor 4 allergy aryl-hydrocarbon receptor indoleamine 2,3-dioxygenase mannose receptor nuclear factor κB