换一批
换一批Fucoidan protects hepatocytes from apoptosis and inhibits invasion of hepatocellular carcinoma by up-regulating p42/44 MAPK-dependent NDRG-1/CAP43.
作者：
关键词
BA, bile acidCXCL, chemokine ligandCultured hepatocyteDISC, death-inducing signaling complexDMEM, Dulbecco?s modified Eagle?s mediumDNA, deoxyribonucleic acidELISA, enzyme-linked immunosorbent assayFADD, Fas associated death domainFBS, fetal bovine serumFCS, fetal calf serumFucoidanGAPDH, glyceraldehyde-3-phosphate dehydrogenaseGP, glypicanHCC, hepatocellular carcinomaHepatocellular carcinomaHepatoprotectiveHypoxiaIHC, immunohistochemistryInvasionJNK, c-Jun NH2-terminal kinaseMAPK, mitogen-activated protein kinaseMTS, 3,4-(5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium saltNDRG, N-myc downstream-regulated geneNDRG-1/CAP43PCR, polymerase chain reactionRNA, ribonucleic acidSD, standard deviationSDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresisVMP, vacuole membrane proteinVMP-1WME, William's medium EcDNA, complementary DNAsiRNA, small interfering RNA
DOI
10.1016/j.apsb.2015.09.004
PMID
26713269
发布时间
2020-10-01
- 浏览46
Acta pharmaceutica Sinica. B
2015年5卷6期
544-53页
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