Relationship of immunohistochemistry, copy number aberrations and epigenetic disorders with BRCAness pattern in hereditary and sporadic breast cancer.

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作者： Rosa,Murria Estal ^[1] ; Sarai,Palanca Suela ^[1] ; Inmaculada,de Juan Jiménez ^[1] ; Cristina,Alenda Gonzalez ^[2] ; Cecilia,Egoavil Rojas ^[2] ; Zaida,García-Casado ^[3] ; Jose Antonio,López Guerrero ^[3] ; María José,Juan Fita ^[4] ; Ana Beatriz,Sánchez Heras ^[5] ; Ángel,Segura Huerta ^[6] ; Ana,Santaballa Bertrán ^[7] ; Isabel,Chirivella González ^[8] ; Marta,Llop García ^[1] ; Gema,Pérez Simó ^[1] ; Eva,Barragán González ^[1] ; Pascual,Bolufer Gilabert ^[9]

作者单位： Laboratory of Molecular Biology, Service of Clinical Analysis, University Hospital La Fe, Torre A 4ª planta, Avenida de Fernando Abril Martorell, no 106, 46026, Valencia, Spain. ^[1] Department of Pathology, University General Hospital, Alicante, Spain. ^[2] Laboratory of Molecular Biology, IVO, Valencia, Spain. ^[3] Department of Oncology, IVO, Valencia, Spain. ^[4] Genetic Counseling Unit, Elche Hospital, Alicante, Spain. ^[5] Genetic Counseling Unit, University Hospital La Fe, Valencia, Spain. ^[6] Department of Oncology, University Hospital La Fe, Valencia, Spain. ^[7] Genetic Counseling Unit, Clinic University Hospital, Valencia, Spain. ^[8] Laboratory of Molecular Biology, Service of Clinical Analysis, University Hospital La Fe, Torre A 4ª planta, Avenida de Fernando Abril Martorell, no 106, 46026, Valencia, Spain. bolufer_pas@gva.es. ^[9]

关键词 BRCAness Copy number aberrations Immunohistochemical markers Promoter methylation microRNA expression