Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.
第一作者:
Jonine D,Figueroa
第一单位:
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA, Usher Institute of Population Health Sciences and Informatics, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK, jonine.figueroa@ed.ac.uk.
作者:
Jonine D,Figueroa [1]
;
Candace D,Middlebrooks [2]
;
A Rouf,Banday [2]
;
Yuanqing,Ye [3]
;
Montserrat,Garcia-Closas [4]
;
Nilanjan,Chatterjee [2]
;
Stella,Koutros [2]
;
Lambertus A,Kiemeney [5]
;
Thorunn,Rafnar [6]
;
Timothy,Bishop [7]
;
Helena,Furberg [8]
;
Giuseppe,Matullo [9]
;
Klaus,Golka [10]
;
Manuela,Gago-Dominguez [11]
;
Jack A,Taylor [12]
;
Tony,Fletcher [13]
;
Afshan,Siddiq [14]
;
Victoria K,Cortessis [15]
;
Charles,Kooperberg [16]
;
Olivier,Cussenot [17]
;
Simone,Benhamou [18]
;
Jennifer,Prescott [19]
;
Stefano,Porru [20]
;
Colin P,Dinney [21]
;
Núria,Malats [22]
;
Dalsu,Baris [2]
;
Mark P,Purdue [2]
;
Eric J,Jacobs [23]
;
Demetrius,Albanes [2]
;
Zhaoming,Wang [24]
;
Charles C,Chung [25]
;
Sita H,Vermeulen [5]
;
Katja K,Aben [5]
;
Tessel E,Galesloot [5]
;
Gudmar,Thorleifsson [6]
;
Patrick,Sulem [6]
;
Kari,Stefansson [26]
;
Anne E,Kiltie [27]
;
Mark,Harland [7]
;
Mark,Teo [28]
;
Kenneth,Offit [29]
;
Joseph,Vijai [29]
;
Dean,Bajorin [30]
;
Ryan,Kopp [31]
;
Giovanni,Fiorito [9]
;
Simonetta,Guarrera [9]
;
Carlotta,Sacerdote [32]
;
Silvia,Selinski [10]
;
Jan G,Hengstler [10]
;
Holger,Gerullis [33]
;
Daniel,Ovsiannikov [34]
;
Meinolf,Blaszkewicz [10]
;
Jose Esteban,Castelao [35]
;
Manuel,Calaza [36]
;
Maria Elena,Martinez [37]
;
Patricia,Cordeiro [38]
;
Zongli,Xu [39]
;
Vijayalakshmi,Panduri [12]
;
Rajiv,Kumar [40]
;
Eugene,Gurzau [41]
;
Kvetoslava,Koppova [42]
;
H Bas,Bueno-De-Mesquita [43]
;
Börje,Ljungberg [44]
;
Françoise,Clavel-Chapelon [45]
;
Elisabete,Weiderpass [46]
;
Vittorio,Krogh [47]
;
Miren,Dorronsoro [48]
;
Ruth C,Travis [49]
;
Anne,Tjønneland [50]
;
Paul,Brennan [51]
;
Jenny,Chang-Claude [40]
;
Elio,Riboli [14]
;
David,Conti [52]
;
Marianna C,Stern [52]
;
Malcolm C,Pike [7]
;
David,Van Den Berg [52]
;
Jian-Min,Yuan [53]
;
Chancellor,Hohensee [16]
;
Rebecca P,Jeppson [16]
;
Geraldine,Cancel-Tassin [54]
;
Morgan,Roupret [55]
;
Eva,Comperat [56]
;
Constance,Turman [57]
;
Immaculata,De Vivo [58]
;
Edward,Giovannucci [59]
;
David J,Hunter [60]
;
Peter,Kraft [61]
;
Sara,Lindstrom [57]
;
Angela,Carta [20]
;
Sofia,Pavanello [62]
;
Cecilia,Arici [20]
;
Giuseppe,Mastrangelo [62]
;
Ashish M,Kamat [21]
;
Liren,Zhang [3]
;
Yilei,Gong [3]
;
Xia,Pu [3]
;
Amy,Hutchinson [24]
;
Laurie,Burdett [24]
;
William A,Wheeler [63]
;
Margaret R,Karagas [64]
;
Alison,Johnson [65]
;
Alan,Schned [64]
;
G M,Monawar Hosain [66]
;
Molly,Schwenn [67]
;
Manolis,Kogevinas [68]
;
Adonina,Tardón [69]
;
Consol,Serra [70]
;
Alfredo,Carrato [71]
;
Reina,García-Closas [72]
;
Josep,Lloreta [73]
;
Gerald,Andriole [74]
;
Robert,Grubb [74]
;
Amanda,Black [2]
;
W Ryan,Diver [23]
;
Susan M,Gapstur [23]
;
Stephanie,Weinstein [2]
;
Jarmo,Virtamo [75]
;
Christopher A,Haiman [76]
;
Maria Teresa,Landi [2]
;
Neil E,Caporaso [2]
;
Joseph F,Fraumeni [2]
;
Paolo,Vineis [77]
;
Xifeng,Wu [3]
;
Stephen J,Chanock [2]
;
Debra T,Silverman [2]
;
Ludmila,Prokunina-Olsson [2]
;
Nathaniel,Rothman [2]
作者单位:
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA, Usher Institute of Population Health Sciences and Informatics, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK, jonine.figueroa@ed.ac.uk.
[1]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
[2]
Department of Epidemiology, MD Anderson Cancer Center, Houston, TX, USA.
[3]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA, Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
[4]
Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
[5]
deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
[6]
Section of Epidemiology and Biostatistics.
[7]
Department of Epidemiology and Biostatistics.
[8]
Department of Medical Sciences, University of Turin, Turin, Italy, Human Genetics Foundation, Turin, Italy.
[9]
Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.
[10]
Genomic Medicine Group, Galician Foundation of Genomic Medicine, Servicio Galego de Saude (SERGAS), Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain.
[11]
Epidemiology Branch, National Institute of Environmental Health Sciences (NIEHS), Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, NC, USA.
[12]
London School of Hygiene and Tropical Medicine, London, UK.
[13]
School of Public Health.
[14]
Department of Preventive Medicine, USC Keck School of Medicine, Department of Obstetrics and Gynecology, Norris Comprehensive Cancer Center, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
[15]
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
[16]
Department of Urology, Tenon, Centre de Recherche sur les Pathologies Prostatiques, Paris, France, UPMC Univ Paris 06, GRC n°5, ONCOTYPE-URO, Paris, France.
[17]
Institut national de la sante et de la recherche medicale, U946, Foundation Jean Dausset Centre d'Etude du Polymorphisme Humain (CEPH), Paris, France, Centre National de la Receherche Scientifique, UMR8200, Institut Gustave-Roussy, Villejuif, France.
[18]
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Department of Epidemiology.
[19]
Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
[20]
Department of Urology, MD Anderson Cancer Center, Houston, TX, USA.
[21]
Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
[22]
Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA.
[23]
Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MD, USA.
[24]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA, Department of Urology, MD Anderson Cancer Center, Houston, TX, USA.
[25]
deCODE Genetics/Amgen, Inc., Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
[26]
CRUK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.
[27]
Radiotherapy Research Group, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds LS9 7TF, UK.
[28]
Department of Medicine.
[29]
Genitourinary Oncology Service, Division of Solid Tumor Oncology, Department of Medicine.
[30]
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[31]
Cancer Epidemiology, CPO Piemonte, Turin, Italy.
[32]
University Hospital for Urology, Klinikum Oldenburg, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany, Department of Urology, Lukasklinik Neuss, Germany.
[33]
Department of Urology, St. Josefs Hospital, Dortmund-Hörde, Germany.
[34]
Oncology and Genetics Unit, Complejo Hospitalario, Instituto de Investigacion Biomedica (IBI) Orense-Pontevedra-Vigo, Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain.
[35]
Genomic Medicine Group, Galician Foundation of Genomic Medicine, Servicio Galego de Saude (SERGAS), Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, Galicia, Spain.
[36]
Department of Family Medicine and Public Health, Moores Cancer Center, University of California San Diego, San Diego, CA, USA.
[37]
Department of Urology, Complejo Hospitalario, University of Santiago de Compostela, Servicio Galego de Saude (SERGAS), Santiago de Compostela, Spain.
[38]
Epidemiology Branch, National Institute of Environmental Health Sciences (NIEHS).
[39]
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[40]
Environmental Health Center, Cluj, Romania.
[41]
State Health Institute, Banska Bystrica, Slovakia.
[42]
School of Public Health, Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands, Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
[43]
Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea University, Umea, Sweden.
[44]
Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health team, Villejuif F-94805, France, Université Paris Sud, UMRS 1018, Villejuif F-94805, France, Institut Gustave Roussy, Villejuif F-94805, France.
[45]
Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway, Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland.
[46]
Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
[47]
Health Department, BioDonostia Research Institute, Basque Region, Spain, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
[48]
Cancer Epidemiology Unit, University of Oxford, Oxford, UK.
[49]
Danish Cancer Society Research Center, Copenhagen, Denmark.
[50]
International Agency for Research on Cancer (IARC), Lyon, France.
[51]
School of Public Health, Department of Obstetrics and Gynecology.
[52]
University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
[53]
Centre de Recherche sur les Pathologies Prostatiques, Paris, France, UPMC Univ Paris 06, GRC n°5, ONCOTYPE-URO, Paris, France.
[54]
Department of Urology, Pitié-Salpétrière, Centre de Recherche sur les Pathologies Prostatiques, Paris, France, UPMC Univ Paris 06, GRC n°5, ONCOTYPE-URO, Paris, France.
[55]
Department of Pathology, Pitié-Salpétrière, Assistance-Publique Hôpitaux de Paris (APHP), Paris, France, Centre de Recherche sur les Pathologies Prostatiques, Paris, France, UPMC Univ Paris 06, GRC n°5, ONCOTYPE-URO, Paris, France.
[56]
Department of Epidemiology.
[57]
Norris Comprehensive Cancer Center, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA, Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
[58]
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Department of Epidemiology, Department of Nutrition.
[59]
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Department of Epidemiology, Department of Nutrition, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
[60]
Department of Epidemiology, Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA.
[61]
Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
[62]
Information Management Services, Silver Spring, MD, USA.
[63]
Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.
[64]
Vermont Cancer Registry, Burlington, VT, USA.
[65]
New Hampshire State Cancer Registry, Concord, NH, USA.
[66]
Maine Cancer Registry, Augusta, ME, USA.
[67]
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain, Municipal Institute of Medical Research, (IMIM-Hospital del Mar), Barcelona, Spain, National School of Public Health, Athens, Greece.
[68]
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
[69]
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain, Municipal Institute of Medical Research, (IMIM-Hospital del Mar), Barcelona, Spain, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.
[70]
Ramon y Cajal University Hospital, IRYCIS, Madrid, Spain.
[71]
Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Spain.
[72]
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
[73]
Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, MO, USA and.
[74]
Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.
[75]
Department of Obstetrics and Gynecology.
[76]
Human Genetics Foundation, Turin, Italy, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
[77]
主题词
病例对照研究(Case-Control Studies);染色体, 人, 13对(Chromosomes, Human, Pair 13);染色体, 人, 20对(Chromosomes, Human, Pair 20);女(雌)性(Female);遗传关联研究(Genetic Association Studies);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans);连锁不平衡(Linkage Disequilibrium);男(雄)性(Male);多态性, 单核苷酸(Polymorphism, Single Nucleotide);危险因素(Risk Factors);膀胱肿瘤(Urinary Bladder Neoplasms)
DOI
10.1093/hmg/ddv492
PMID
26732427
发布时间
2024-03-24
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Human molecular genetics
Human molecular genetics
1203-14页
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